Background: Spinal cord injury (SCI) is a major clinical condition and research is commonly done to find suitable treatment options. However, there are some degrees of spontaneous recovery after SCI and gender is said to be a contributing factor in recovery, but this is controversial. This study was done to compare the effects of sexual dimorphism on spontaneous recovery after spinal cord inj...

stem cell therapy can be useful for spinal cord injury (sci). induced pluripotent stem cells (ipscs) are generated by reprogramming mature, fully differentiated cells into a pluripotent state. the ability to generate pluripotent cells from adult somatic cells without the need for an embryo was a major development in stem cell biology. ipscs were established from mouse fibroblasts and demonstrat...

objective(s) recent studies revealed the neuroprotective effects of epigallocatechin gallate (egcg) on a variety of neural injury .the purpose of this study was to determine the effects of egcg on the tissue lipid peroxidation after spinal cord injury (sci). materials and methods rats were randomly divided into four groups of 7 rats each as follows: sham-operated group, trauma group, and egcg-t...

F a c u l t y M e n t o r Michelle Tu’s interest in stem cells began when she read about the promise of stem cell research; she was amazed by their unique features, especially their ability to differentiate into any cell type in the body. She was drawn to Professor Keirstead’s study on humanembryonic stem cell-derived oligodendrocyte progenitor cells in spinal cord injury. Michelle describes he...

Traumatic injuries to the brain and spinal cord affect a large percentage of the world's population. However, there are currently no effective treatments for these central nervous system (CNS) injuries. In our study, we evaluated the neuroprotective role of functionalized multi-walled carbon nanotubes (MWCNTs) carrying brain derived neurotrophic factor (BNDF), nogo-66 receptor (NgR) and Ras hom...

OBJECTIVE To describe the demography, types of injuries and their management in all non-disaster spinal injury patients admitted to the Spine Unit of a tertiary care hospital in Pakistan from 2001-2008. STUDY DESIGN Case series. PLACE AND DURATION OF STUDY Spine Unit, Orthopaedic Department, Combined Military Hospital, Rawalpindi, from April 2001 to December 2008. METHODOLOGY Data of all ...

Abstract In this review article, we present more than a decade of our work on the development brain–computer interface (BCI) systems for restoration walking following neurological injuries such as spinal cord injury (SCI) or stroke. Most has been in domain non-invasive electroencephalogram-based BCIs, including interfacing system with virtual reality environment and physical prostheses. Real-ti...