Accommodation services oriented to different tourist segments usually have price determinants. Thus, in multi-facet destinations such as large regions or cities, it should be possible find and describe the underlying types of tourism destination by using a determinant analysis. In this paper, methodology based on stepwise geographically weighted regression (GWR) is developed, k-means clustering...

1 Potsdam Institute for Climate Impact Research, Germany 10 2 School of Geography, University of Nottingham, UK 11 3 NASA Goddard Institute for Space Studies, USA 12 4 Center for Climate Systems Research, Columbia University, USA 13 5 Faculty of Geosciences, Utrecht University, The Netherlands 14 6 Swedens Meteorological and Hydrological Institute, Sweden 15 7 Max Planck Institute for Meteorolo...

The central thesis of the 2005 Anderson Lecture is that significant achievements in applied geography occur when the principles and practices of curiosity-driven and client-driven research are combined in the statement of problem, the idealized and operational research design, and the procedures of evaluating results. A companion thesis extends the Anderson Lectures by Jack Dangermond, Brian Be...

Fragile X Syndrome (FXS) is caused by an expansion of CGG trinucleotide repeats in the 5′ untranslated region of the Fragile X mental retardation 1 (FMR1) geneon theXchromosome.Affected individuals possess over 200 copies of the CGG repeat, resulting in hypermethylation of the FMR1 promoter, which leads to epigenetic silencing of the gene and FMRP protein deficiency. Children with FXS display i...

In February 2006, a patient colonized with a multidrug-resistant sequence type 56 Acinetobacter baumannii strain was admitted to a hospital in Madrid, Spain. This strain spread rapidly and caused a large outbreak in the hospital. Clinicians should be alert for this strain because its spread would have serious health consequences.

a Department of Geography, Texas Center for Geographic Information Science, 601 University Drive, Texas State University, San Marcos, San Marcos, TX 78666, United States b Department of Geography, McClure Hall 203, P.O. Box 443021, University of Idaho, Moscow, ID 83844, United States c Rocky Mountain Research Station, US Department of Agriculture Forest Service, 1221 South Main Street, Moscow, ...