Plasma clearance of D-sorbitol, a nontoxic polyol, occurs predominantly in the liver and has been used to measure functional liver blood flow after bolus and steady- state intravenous administration. However, it is not known which of these two administration methods is superior. Therefore, plasma D-sorbitol clearance was studied in an animal model both after a bolus dose and under steady-state ...

Sorbitol is one of the platform chemicals and can be produced from various renewable sustainable sources via different processes. Hydrothermal liquefaction an effective promising approach to produce sorbitol, since subcritical reaction media appropriate catalysts provide a selective production chemicals. In this study, sorbitol was (cellulose glucose) in presence Ru-based (Ru/SiO2, Ru/AC, Ru/SB...

Potassium tellurite was assessed for the selection of verocytotoxigenic (VT+) Escherichia coli O157. MICs were higher for VT+ E. coli O157 than for other strains of E. coli and for Aeromonas spp. MacConkey medium containing sorbitol, tellurite and cefixime (TC-SMAC) permitted the growth of VT+ E. coli O157 and Shigella sonnei but partially or completely inhibited the growth of 67% of other stra...

The present study determined the effect of different types of sugars (lactose, fructose, glucose and sorbitol) used in egg yolk-based extender on the post-thawed boar semen quality. Twenty-two ejaculates from 6 fertility-proven Yorkshire boars were cryopreserved by liquid nitrogen vapor method. Sperm motility, viability, acrosome integrity and intact functional plasma membrane were determined a...

Fructose and sorbitol accumulate in the aging rat lens, the levels rising from values of 7 and 17 mg. per 100 Gin. wet lens weight, respectively, in weanlings, to 27 and 34 mg. per 100 Gm. in 200-day-old animals. The formation of fructose and sorbitol from glucose via the sorbitol pathway apparently decreases with age. Penetration of the lens in vitro by fructose-U-C-14 decreases with age. Furt...

background: poisoning, a common worldwide problem, seeks its own treatments to improve, especially by the forthcoming evidence based medicine (ebm). charcoal/sorbitol slurry (css) administration is one of these methods with great debates around it which needs to be investigated more. methods: in this clinical trial, 105 cases of benzodiazepine toxicity with at least 3 symptoms and no contraindi...

Recombinant protein production in Pichia pastoris is based on alcohol oxidase promoterswhich are regulated by methanol. However, the use of methanol has several disadvantages,which is why current trends in bioprocess development with Pichia pastoris (P. pastoris) arefocusing on methanol mixed feeding strategies. This work aimed to develop a new experimentalmethod and compare the effect of vario...

Changes in microbial community structure are widely known to occur after soil amendment with low-molecular-weight organic compounds; however, there is little information on concurrent changes in soil microbial functional diversity and enzyme activities, especially following sorbitol and mannitol amendment. Soil microbial functional diversity and enzyme activities can be impacted by sorbitol and...

The activity of the enzymes, aldose reductase and polyol dehydrogenase, associated with sorbitol pathway were determined in the rabbit ciliary body and compared with the activity of these enzymes in the lens and the retina, a tissue which has the same embryologic origin as the ciliary body. Despite the presence of the two enzymes, no sorbitol could be detected in the ciliary body of diabetic ra...

conclusions these results demonstrated that cse, mainly through inhibition of alr2, could prevent or delay the diabetic complications, like cataract formation, as a result of sorbitol accumulation. results the cse inhibited alr2 activity, with an ic50 of 0.54 mg/ml and it was seven and a half times greater than that of alr1 inhibition, indicating the specificity of cse for alr2, rather than alr...