PURPOSE The purpose of this article is to evaluate patients' visual acuity, symptoms, and perceptions of vision-related quality of life in a randomized crossover clinical trial of overnight corneal reshaping (OCR) and daily wear soft lenses (SCL). METHODS Qualified subjects were randomly assigned to wear one mode of contact lens for 8 weeks and then, after a washout period, they wore the alte...

PURPOSE To evaluate the impact of disposable soft contact lenses upon visual performance by comparing the optical aberrations of myopic eyes with and without the use of contact lenses. METHOD The optical aberrations of a set of 18 eyes were measured by a laser ray tracing system, an objective measurement method, enabling comparison of the findings of the naked eye, the eye plus a test lens, a...

PURPOSE Weekly disposable soft contact lenses have been widely used recently, but their shield effects against ultraviolet (UV) irradiation remain to be evaluated. This study investigated the bioprotective effects of several weekly soft contact lenses against UVB irradiation on the corneal surface in a mouse model. METHODS Fifty ICR mice were randomly divided into five groups: (1) blank contr...

PURPOSE To evaluate the displacement of the central ocular surface during non-contact tonometry with and without soft contact lenses and determine the factors associated with the displacement of the central ocular surface and intraocular pressure (IOP) reading changes caused by wearing soft contact lenses (CLs). METHODS One eye each in 21 subjects was studied. The cornea was photographed usin...

Microorganisms, especially gram-negative bacteria, are considered to play a role in the etiology of certain corneal infiltrative events (CIEs) observed during soft contact lens wear. This study explored the possibility of microbial colonization of soft contact lenses as a risk factor leading to CIEs. In a clinical trial conducted from March 1993 to January 1996, 330 subjects wore disposable sof...