Aldosterone production following ACTH administration has been shown to be enhanced in sodium depletion. The mechanism(s) for this, however, is not entirely clear. Meanwhile, prostaglandins of the E series have been shown to stimulate steroidogenesis and urinary excretion of prostaglandin E2 and F2a in man, and PGI2 in the aortic wall of rats has been shown to increase in sodium depletion. In vi...

Boron Neutron Capture Therapy (BNCT) effectiveness depends on the preferential sequestration of boron in cancer cells relative to normal tissue cells. We present a novel strategy for sequestering boron using an adenovirus expressing the sodium iodide symporter (NIS). Human glioma grown subcutaneously in athymic mice and orthotopic rat brain tumors were transfected with NIS using a direct tumor ...

Z. Naturforsch. 56 b, 1257-1263 (2001); received September 11, 2001 Gold(I) Complexes, Tri(tertiary phosphine) Complexes, Thiolate Complexes Treatment of the ligand l,3,5-tris[(diphenylphosphanyl)methyl]trimethylbenzene (P3) with (tetrahydrothiophene)gold(I) chloride results in the symmetrical trigold complex [(P3)(AuC1)3]. In the presence of sodium methoxide, [(P3)(AuC1)3] reacts with thiocres...

A simple, sensitive, and convenient spectrophotometric method for the determination of diclofenac sodium and piroxicam in pure form and in pharmaceutical formulations was developed. The method is based on the oxidation of diclofenac sodium or piroxicam by iron(III) in the presence of o-phenanthroline. The formation of tris(o-phenanthroline) iron(II) complex (ferroin) upon the reaction of diclof...

an animal model was designed to study the effect of large volume hypertonic solutions (hts) for re suscitation following a hypovolemic shock. resuscitation in hypovolemic animals was performed by infusion of 15 ml/kg of normal saline (group i), 5% sodium bicarbonate (nahco3) (group ii), 5% sodium chloride (naci) and 7.5 % nahco3 1:1 vn (group iii), 5% nac1 (group iv), and 5% nacl and 5% serum a...

The one-pot condensation of glyoxal, two equivalents of cyclohexylamine, and paraformaldehyde in the presence of aqueous HBF4 provided a straightforward access to 1,3-dicyclohexylimidazolium tetrafluoroborate (ICy·HBF4). 1,3-Dibenzylimidazolium tetrafluoroborate (IBn·HBF4) was obtained along the same lines. To synthesize 1,3-diarylmidazolium salts, it was necessary to isolate the intermediate N...