A bstract. Consumption of alcohol causes hyperuricemia by decreasing urate excretion and increasing its production. Our previous studies indicate that ethanol administration increases uric acid production by increasing ATP degradation to uric acid precursors. To test the hypothesis that ethanol-induced increased urate production results from acetate metabolism and enhanced adenosine triphosphat...

The current studies were performed to better understand the physiological relevance of acetate in the poorly ketogenic piglet and to determine if endogenous acetogenesis rises with increased mitochondrial fatty acid β-oxidation, analogous to ketogenesis. Plasma acetate concentration values in newborn, fasted, or suckled piglets (230-343 μM) were at least 10-fold higher than the ketone bodies, a...

Short-chain fatty acid (SCFA) concentrations of intestinal contents from the herbivorous tilapia, Oreochromis mossambicus, were analysed by gas and high-performance liquid chromatography. Concentrations of acetate ranging from 3 to 18 mmol l-1 were found along the full length of the intestinal tract, as were trace amounts of propionate. Characteristics of [3H]acetate transport by the intestinal...

Acetate and propionate, produced during colonic fermentation of unabsorbed carbohydrate, may influence systemic lipid metabolism. As a preliminary study to see whether colonic acetate is incorporated into plasma lipids and whether propionate inhibits this process, 5 healthy males were studied after fasting overnight. They were given, in random order, 12.5 mmol (1.05 g) [1,2-13C]sodium acetate b...

calcium acetate is used as an oral phosphate binder to control hyperphosphatemia in patients with chronic renal failure. compared to calcium carbonate, control of hyperphosphatemia can be achieved at lower calcium administration with calcium acetate which likely reduces the risk of hypercalcemia. in this study, various formulations of calcium acetate tablets were prepared and their disintegrati...

poly-β-hydroxybutyrate (phb), produced by several species of bacteria, has attracted great attention as a biodegradable and biocompatible compound with almost similar properties of polypropylene. unfortunately, its use is currently limited due to high production costs. one of the most common methods for overcoming this constraint is the use of inexpensive substrates, like methanol. another stra...

Hydrogen sulphide production by growing cultures and non-multiplying suspensions was compared and the factors influencing the sensitivity of the tests were investigated. Cysteine hydrochloride (0.01 yo) was added to Lemco broth to provide a medium with a standard source of sulphur. H,S was detected with lead acetate papers more readily than by lead acetate agar. Suspensions were tested with cys...