INTRODUCTION A controversial aspect of breast cancer management is the use of sentinel lymph node biopsy (SLNB) in patients requiring neoadjuvant chemotherapy (NCT). This paper discusses the detection rate (DT) and false negatives (FN) of SLNB after NCT to investigate the influence of initial nodal disease and the protocols applied. METHODS Prospective observational multicenter study in women...

Results: The median disease-free interval of 35 patients with IBTR was 66.7 month and the median tumor size of IBTR was 1.2cm. A total of 22 patients had previous SLNB, 8 patients had previous axillary lymph node dissection (ALND), and 5 patients had no previous axillary treatment. The average number of lymph nodes harvested at the time of primary surgery with SLNB and ALND was 2.9 and 20.8, re...

This study is to investigate the accuracy of Sentinel Lymph Node Biopsy (SLNB) in predicting axillary lymph node metastasis and its application in breast conserving surgery for early breast cancer. The clinical data of SLNB of 448 patients were retrospectively analyzed. The patients with negative result of SLNB were not performed with Axillary Lymph Node Dissection (ALND) (experimental group), ...

Sentinel lymph node biopsy (SLNB) is a sensitive operation for finding micro-metastasis in patients with cutaneous melanoma without evidence of clinically positive lymph node findings. However, until now, no clinical trials or retrospective studies with large samples have been performed to investigate the clinical role of SLNB for cutaneous melanoma patients. In this study, we used the data of ...

Cutaneous melanoma clinical practice guidelines generally recommend a 10% risk threshold to offer sentinel lymph node biopsy (SLNB), with improved stratification desirable reduce unnecessary procedures. A retrospective analysis was conducted among patients undergoing SLNB at an academic center between June 2010 and December 2021 compare rates of SLN-positivity the validated Melanoma Institute A...

The application and utility of melanoma sentinel lymph node biopsy (SLNB) has evolved significantly since its inception over two decades ago. The current focus has shifted from a staging modality to potentially a therapeutic intervention. Recent research to include large multi-institutional randomized trials have attempted to answer the question: is a completion lymph node dissection (CLND) req...

OBJECTIVE To analyze the rate of axillary recurrences (AR) in patients with early breast cancer who had not undergone an axillary node dissection (ALND) because of a negative sentinel lymph node biopsy (SLNB). MATERIAL AND METHODS The study includes 173 patients operated on for breast cancer and selective node biopsy. In 32 patients the SLNB was positive and undergone subsequent ALND. We foll...

The aim of this study was to compare the incidence of lymphoedema after different treatments of the axilla in patients with breast cancer (BC). Medical records of 205 women (median age 61 years, range 26-72 years) who underwent curative surgery for primary BC were reviewed. According to the treatment of the axilla, the study population was divided into four age- and stage-matched groups of pati...

BACKGROUND Sentinel lymph node biopsy (SLNB) has become the standard care for melanoma and is an important diagnostic procedure. It has been doubted whether lymphoscintigraphy detects the correct sentinel lymph node (SLN) when excision of the tumor and SLNB are not performed at the same time. This would imply that this sequential approach may have an increased risk of undetected micrometastases...

BACKGROUND Sentinel lymph node biopsy (SLNB) is rapidly becoming the standard of care in the treatment of women with early stage breast cancer. Male breast cancer although relatively rare, has typically been treated with mastectomy and axillary lymph node dissection (ALND). Men who develop breast carcinoma have the same risk as their female counterparts of developing the morbidities associated ...