BACKGROUND The free anterolateral thigh (ALT) flap has been widely used for various kinds of reconstructions. However, delayed healing at the donor site occasionally occurs due to wound dehiscence or the partial loss of grafted skin at the donor site. The aim of the present study was to identify reliable predictive factors for delayed healing at the donor site after the harvest of a free ALT fl...

background: skin flap grafting is a popular approach for reconstruction of critical skin and underlying soft tissue injuries. in a previous study, we demonstrated the beneficial effects of two 5α-reductase inhibitors, azelaic acid and finasteride, on tissue survival in a rat model of skin flap grafting. in the current study, we investigated the involvement of nitric oxide and inducible nitric o...

Abstract Case A 74-year-old female patient presented with severe osteoarthritis and pathological fracture of the left knee, following treatment radiotherapy osteosarcoma over a decade ago. Surgical management was initially not possible, due to radiation-induced fibrosis skin. She referred plastic surgery department where she underwent total three sessions fat grafting nine months. The rigotomy ...

Introduction: Skin graft reconstruction is a common method of providing wound coverage. Rarely, skin grafting can be associated with the development squamous cell carcinoma (SCC) in donor site. Case Report: The patient 72-year old male 15-year history bilateral hip wounds. He underwent multitude treatments previously failed reconstructive efforts. After presenting to us, he multiple debridement...

We describe the case of a two-year-old boy with massive burns. After the period of shock and sepsis, very successful four-phase operative treatment was performed, with combined skin grafting homograft plus autograft. With regard to the four surgical interventions, in the first two we used the above combined method, while in the other two we used grafting only with skin autograft. We also used t...

Autologous skin-grafting is the gold standard for treatment of deep second and third degree burns. Available bioengineered skin products also necessitate this two-step surgical procedure. Therefore, we developed fetal skin constructs to improve healing of such degree burns. A bank of fetal skin cells was developed from one organ donation (4 cm2 of skin allowing the preparation of several millio...

Over the last decade, lymph node flap (LNF) transfer has turned out to be an effective method in the management of lymphoedema of extremities. Most of the time, the pockets created for LNF cannot be closed primarily and need to be resurfaced with split thickness skin grafts. Partial graft loss was frequently noted in these cases. The need to prevent graft loss on these iatrogenic wounds made us...

Little is known about the use of dermoscopy in skin grafting. We describe the case of a patient with skin grafting and surrounding pigmentation on acral region. The dermoscopic findings were similar to those of benign acral lesions (lattice-like pattern) and reactive pigmentations (fine striae). Histopathology revealed pigment leakage and increased number of melanocytes. It is believed that thi...

OBJECTIVE To observe the effects of low intensity laser therapy in inflammation, wound healing and epithelialization of island skin grafts. METHODS Twenty rats were subjected to this grafting technique and divided subsequently into two equal groups, one treated with laser and the other control. RESULTS there was less inflammation, faster healing, epithelialization and keratinization in the ...