This paper presents the performance evaluation of eight focus measure operators namely Image CURV (Curvature), GRAE (Gradient Energy), HISE (Histogram Entropy), LAPM (Modified Laplacian), LAPV (Variance of Laplacian), LAPD (Diagonal Laplacian), LAP3 (Laplacian in 3D Window) and WAVS (Sum of Wavelet Coefficients). Statistical matrics such as MSE (Mean Squared Error), PNSR (Peak Signal to Noise R...