Situs inversus totalis (SIT) denotes complete right-left inversion of the thoracic and abdominal viscera. Diagnosis and surgical procedures for abdominal pathology in patients with SIT are technically more complicated because of mirror-image transposition of the visceral organs. Moreover, SIT is commonly associated with cardiovascular and hepatobiliary malformations, which make hepatobiliary-pa...

Humans do not only perform individual motion separately, but they transit motions from one to another. It has been widely known that human sit-to-stand and walking motions are composed of four and five muscle synergies, but it is not clarified how humans utilize these muscle synergies to generate sit-to-walk motion. This study conducted a measurement experiment to identify muscle synergy struct...

BACKGROUND Allergic asthma is a T(H)2 inflammatory disease. Dendritic cells (DCs) play key roles in the T(H)1/T(H)2 balance. Allergen specific immunotherapy (SIT) has the potential to modify the course of allergy because the ratio of T(H)1 to T(H)2 cytokines produced is increased after SIT. OBJECTIVE To determine how SIT affects DCs in children and to define novel parameters of this treatment...

AWIS President Susan M. Fitzpatrick can be contacted at [email protected] In 1923 a young woman named Susan Gill left her home in Ireland for New York City. Like many of the “greenhorn” girls making a similar transition to the new country from the old, she first found work as a housekeeper, and eventually transitioned to a position working the night shift at the Tetley tea bag factory. Her husband...

Individuals diagnosed with the metabolic syndrome (MetS) exhibit elevated postprandial lipemia (PPL). The aims of this investigation were to determine 1) if an acute bout of sprint interval training (SIT) attenuates PPL; and 2) if the attenuation of PPL following 6 wk of SIT is magnified compared with a single session of SIT prior to training in women at-risk for MetS (n = 45; 30-65 yr). Women ...

BACKGROUND Specific IgG4 induced by allergen-specific immunotherapy (SIT) is an immunological marker related to the appearance of clinical tolerance. But specific IgG4 levels in different age, gender and allergic disease populations have not been fully investigated. METHODS This study involved 226 children and 109 adults with allergic rhinitis and/or asthma receiving a 156-week course of Derm...

Transmembrane adaptor proteins (TRAPs) organize signaling complexes at the plasma membrane, and thus function as critical linkers and integrators of signaling cascades downstream of antigen receptors. We have previously shown that the transmembrane adaptor protein SIT regulates the threshold for thymocyte selection. Moreover, T cells from SIT-deficient mice are hyperresponsive to CD3 stimulatio...

The aim of this study was to examine the interaction of soybean-derived sterylglucoside (SG) with the human hepatoblastoma cell line HepG2 with regard to the penetration-enhancing effect of beta-sitosterol glucoside (Sit-G) to clarify the accumulation of SG-containing liposomes (SG-liposomes) to the liver in vivo. The approach was based on measurement of the association of SG-liposomes labeled ...