نتایج جستجو برای: signaling pathways
تعداد نتایج: 469190 فیلتر نتایج به سال:
Effects of fibromodulin protein expression on NFkB and TGFβ signaling pathways in liver cancer cells
Introduction: The incidence rate of liver cancer is continuously increasing. Currently, gene therapy is applied to improve various medical issues such as cancer treatment approaches. Correspondingly, fibromodulin involves in many biological and physiological processes through interaction with growth factors and signaling pathway receptors. The aim of this study was to investigate the effects of...
Hair loss is a common hair disorder in human population. It affects quality of life and there are ongoing attempts to find permanent treatment for this condition. But, today there is no completely safe and protective treatment for all. Hair follicle stem cells are alive, but quiescence in androgenetic alopecia and are potentially active and can proliferate and differentiate, then regenerate hai...
Objective(s):Fuzheng Huayu recipe (FZHY) exerts significant protective effects against liver fibrosis by strengthening the body’s resistance and removing blood stasis. However, the molecular mechanisms through which FZHY affects liver fibrosis are still unclear. In this study, we examined the expression levels of factors involved in the inhibitor κB kinase-β (IKK-β)/nuclear factor-κB (NF-κB) an...
Since human beings could travel beyond the earth atmosphere, scientists started to investigate the effect of microgravity on human cells. Microgravity has different effects on normal and cancer cells, but the related mechanisms are not well-known till now. The aim of the present review is to focus on the consequences of exposing the cancer cells to reduced gravity. Some cancer cells organize th...
objective: osteoblasts arise from multipotent mesenchymal stem cells (mscs) present in the bone marrow stroma and undergo further differentiation to osteocytes or bone cells. many factors such as proteins present in the wnt signaling pathway affect osteoblast differentiation. ror2 is an orphan tyrosine kinase receptor that acts as a co-receptor in the non-canonical wnt signaling pathway. howeve...
Long-term potentiation (LTP) is a process that certain types of synaptic stimulation lead to a long-lasting enhancement in the strength of synaptic transmission. Studies in recent years indicate the importance of molecular pathways in the development of memory and learning. Tropomyosin receptor kinase B (TrkB) is a member of the neurotrophin receptor tyrosine kinase family, that its ligand is b...
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