Chris Evelo Head of Department of Bioinformatics, BiGCaT at Maastricht University, The Netherlands Hiroaki Kitano Director of Systems Biology Institute in Tokyo; Professor, Okinawa Institute of Science and Technology Graduate University, Japan Chris Sander Chair of Computational Biology at Sloan-Kettering Institute, New York, New York, USA Josh Stuart Assoc. Professor of Biomedical Engineering ...

Spatial Information Grid (SIG) is a project of applying grid technology to share and integrate spatial data resources, information processing resources, equipment resources, and knowledge resources. SIG computing environment aims to apply the concept of SIG to share hybrid computing resources for processing remote sensing (RS) images. RS image processing is a data-intensive computing problem, a...

The social implications of GIS have been debated over the past five years among scholars in several disciplines. GIS have been either conceived by practitioners as value-free, neutral tools for problemsolving or castigated by critical social theorists as socially biased technologies serving only corporate and state interests. Neither of these polarized views is very helpful in understanding the...

The simultaneous use on mouse lymphoid suspensions of heterologous antisera directed against thymus-derived (T) cell mouse-specific lymphocyte antigen and brain-associated theta antigen (MSLA and BAtheta) or thymus-independent (B) cell mouse-specific bone marrow-derived lymphocyte antigen (MBLA) surface antigens allowed direct proof of the different specificity of these antisera by double immun...

In vitro infection of human B lymphocytes with Epstein-Barr virus (EBV) results in establishment of B lymphoblastoid cell lines that reflect normal B cell phenotypes. In this study we have investigated whether immature B cells from fetal bone marrow and liver can serve as targets for EBV. The fetal bone marrow cells were readily transformed by EBV. Among the resulting cell lines, five were surf...

The monoclonal antibody, RA3-2C2, appears to be specific for cells within the B cell lineage. This antibody does not recognize thymocytes, peripheral T cells, or nonlymphoid hematopoietic cells in the spleen or bone marrow. Nor does it recognize the pluripotent hematopoietic stem cells, the spleen colony-forming unit, All sIg+ B cells and most plasma cells are RA3-2C2+. In addition, approximate...