نتایج جستجو برای: sidestream
تعداد نتایج: 414 فیلتر نتایج به سال:
RATIONALE Smoking during pregnancy increases the risk of bronchopulmonary dysplasia (BPD) and, in mice, gestational exposure to sidestream cigarette smoke (SS) induces BPD-like condition characterized by alveolar simplification, impaired angiogenesis, and suppressed surfactant protein production. Normal fetal development occurs in a hypoxic environment and nicotinic acetylcholine receptors (nAC...
Mainstream and sidestream smoke extracts of both high-tar and low-tar cigarettes have been shown to increase platelet activation directly and to sensitize them to further activation by exposure to mechanical stimuli such as shear stress. However, nicotine has an inhibitory effect on platelet activation, opposite to that of whole cigarette smoke extracts. To distinguish between the nicotine-depe...
We previously found that cigarette sidestream smoke particulate matter (CSSP) could activate estrogen receptor ERα to generate estrogen-like tumor-promoting effects. This study sought identify the compounds responsible for CSSP estrogenicity. first identified component using a combination of GC-MS and mass spectral matching. Based on computational estrogenicity prediction, nine potential estrog...
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