Background: Hemoglobin S arises is the result of a point mutation (A-T) in the sixth codon on the -globin gene on chromosome 11 causing sickle cell anemia. The presence of fetal hemoglobin in infancy plays a relatively protective role for vaso-occlusive symptoms that are the major contributor for the morbidity and mortality among patients with sickle cell anemia. hydroxyurea, an s-phase-specif...

objective:  the aim of this study was to assess clinical laboratory funding for differential diagnosis of sickle cell disease (scd) and other associated disorders for better understanding of clinical types and prevention of sickling events. material and methods:  this is a descriptive crossed-sectional study that analyzed the peripheral blood film, sickle cell preparation, hemoglobin electroph...

VATER association is an exceptionally rare condition; however it is associated with multiple rib anomalies, which is one of its unique presentation. We are reporting a case of VATER associated with rib anomalies in various forms like bifid rib, ribbon rib and rudimentary rib.

We present the design, fabrication and characterization of Bragg reflectors on silicon-on-insulator rib waveguides. The fabrication is based on a new double lithographic process, combining electron-beam lithography for the grating and photolithography for the waveguides. This process allows the realization of low loss reflectors, which were fully characterized. The influence of the etching dept...

A key determinant of overall morphogenesis in flowering plants such as Arabidopsis thaliana is the shoot apical meristem (growing tip of a shoot). Gene regulan'on networks can be used to model this system. We exhibit a very preliminary two.dimensional model including gene regulation and intercellular signaling, but omitting cell division and dynamical geometry. The model can be trained to have ...

conclusions the results of this study showed that self-management interventions are effective in promoting self-efficacy in patients with sickle cell disease. thus, the use of self-management programs is advisable to change behaviors and promote self-efficacy in such patients. background patients with sickle cell disease suffer from various complications during their lifetime. in order to cope ...

Abstract Background: Transcranial Doppler ultrasonography results have not been previously studied in among Iranian sickle cell anemia patients. The present study was performed to evaluate the pattern of intracranial flow velocities among Iranian children with sickle cell anemia and the hematological parameters that can affect the time-averaged mean of maximum velocity in major intracranial...

BACKGROUND First rib fractures are considered indicators of increased morbidity and mortality in major trauma. However, this has not been definitively proven. With an increased use of CT and the potential increase in detection of first rib fractures, re-evaluation of these injuries as a marker for life-threatening injuries is warranted. METHODS Patients sustaining rib fractures between Januar...

conclusions along with the technological advancement, different materials are employed according to the size of the cranium defect and the age of the case. the application of split costa cranioplasty for the small cranium defects in the region of patient’s face is the method with the least possibility of complications, and its cosmetic and functional results are quite promising. introduction os...