256 Cell 124, January 27, 2006 ©2006 Elsevier Inc. The proteasome is a major nonlysosomal proteolytic apparatus that destroys damaged or misfolded proteins as well as regulators governing fundamental cellular processes such as the cell cycle, transcription, cell signaling, cell death, and the immune response (Goldberg, 2003). The catalytic core of this large multisubunit proteolytic complex is ...

This paper presents a comparison of various recovery methods in terms of capacity efficiency with the underlying aim of reducing control plane load. In particular, a method where recovery requests are bundled towards the destination (Shortcut Span Protection) is evaluated can compared against traditional recovery methods. The optimization model is presented and our simulation results show that ...

Various cognitive models have been proposed to determine optimal paths in spatial navigation tasks, some of which demonstrate latent learning in Agents. We view and present the model as a Reinforcement Learning problem by using QLearning and Model-Based Learning in a deterministic environment. This paper uses a QLearning algorithm and compares its performance with the Dyna (Model based) algorit...

Residual networks are the current state of the art on ImageNet. Similar work in the direction of utilizing shortcut connections has been done extremely recently with derivatives of residual networks and with highway networks. This work potentially challenges our understanding that CNNs learn layers of local features that are followed by increasingly global features. Through qualitative visualiz...

Abstract Distributed graph algorithms in the standard CONGEST model often exhibit time-complexity lower bound of $${\tilde{\Omega }}(\sqrt{n} + D)$$ ? ~ ( n + D )</mml:...

In this paper we present imss: IP Multicast Shortcut Service for ATM networks. imss pursues the \short-cut" routing paradigm in order to exploit the underlying ATM QoS and native routing mechanisms in the optimal way. imss is built on top of congress (CONnection oriented Group-address RESolution Service). Congress is an eecient native ATM protocol for resolution and management of multicast grou...

This paper is intended to introduce a graduate student to the speaker verification problem. Knowledge of pioneer work, as well as real methods overview, clears the path into deeper investigation. A list of useful references and books provides further orientation. The panorama is not complete if practical considerations are not taken into account: corpora, assessment of detection performance, sp...

This paper explores the use of heuristics as cognitive strategies invoked during the process of design. Heuristics are reasoning processes that do not guarantee the best solution, but often lead to potential solutions by providing a simple cognitive “shortcut.” We propose that designers use specific design heuristics to explore the problem space of potential designs, leading to the generation o...