We have shown that leukocytes retract their pseudopods and detach from substrates after exposure to physiological fluid shear stresses ( approximately 1.5 dyn/cm(2)). In inflammation, however, pseudopod projection during spreading and firm adhesion on endothelium is observed even in microvessels with normal blood flow and fluid shear stresses. Thus, we examined mechanisms that may serve to regu...

Collocation methods are popular in providing numerical approximations to complicated governing equations owing to their simplicity in implementation. However, point collocation methods have limitations regarding accuracy and have been modified upon with the application of B-spline approximations. The present study reports the stress and deformation behavior of shear deformable functionally grad...

BACKGROUND Adhesive systems are constantly subjected to mechanical and chemical stresses that negatively impact the integrity and durability of the dentine-adhesive interface. Despite the lack of evidence to support or reject the clinical indication for mechanical retention, the potential further contribution of these preparations to the behavior of the composite resin-sound dentine bond has be...

Matrix metalloproteinase (MMP)-1, 2, with their endogenous inhibitors, tissue inhibitor of metalloproteinase (TIMP)-1, 2 are critical for extracellular matrix remodeling in human periodontal ligament (PDL) and their expression are sensitive to mechanical stresses. Shear stress as the main type of mechanical stress in tooth movement is involved in matrix turnover. However, how shear stress regul...

The contour method of residual stress measurement has recently been adapted to measure fractured, rather than cut specimens. The fracture contour method was capable of determining normal residual stresses acting prior to the planestrain failure of a large aluminium alloy forging, but shear residual stresses could not be measured (Prime et al., 2014, Eng. Fract. Mech., 116, 158-171). We demonstr...

Clinically significant atherosclerosis in the human aorta is most common in the infrarenal segment. This study was initiated to test the hypothesis that flowfield properties are closely related to the localization of plaques in this segment of the arterial system. Wall shear stress was calculated from magnetic resonance velocity measurements of pulsatile flow in an anatomically accurate model o...

This paper presents the effect of centrifugal load in functionally graded (FG) hollow sphere subjected to uniform magnetic field. Analytical solution for stresses and perturbation of the magnetic field vector are determined using the direct method and the power series method. The material stiffness, the magnetic permeability and the density vary continuously across the thickness direction accor...

BACKGROUND Stress shielding in the cemented hip prosthesis occurs due to the mismatching in the mechanical properties of metallic stem and bone. This mismatching in properties is considered as one of the main reasons for implant loosening. Therefore, a new stem material in orthopedic surgery is still required. In the present study, 3D finite element modeling is used for evaluating the artificia...

Many fabrication processes for polymeric objects include melt extrusion, in which the molten polymer is conveyed by a ram or a screw and the melt is then forced through a shaping die in continuous processing or into a mold for the manufacture of discrete molded parts. The properties of the fabricated solid object, including morphology developed during cooling and solidification, depend in part ...

ABSTRACT: This paper describes analysis of deep beams subjected to two point loading with three different L/D ratios (1.5, 1.6, 1.71) using Non-linear Finite element method (ANSYS 9.0 software) in order to investigate the stress and strain distribution pattern at mid-section of the beam. In ANSYS 9.0 software, SOLID 65 and LINK 8 element represent concrete and reinforcing steel bars. Non-linear...