The paper draws on in-depth qualitative. comments from student evaluation of an e-learning module on an MSc in Information Technologies and Management, to develop a picture of their perspective on the experience. Questionnaires that yielded some basic quantitative data and a rich seam of qualitative data were administered. General questions on satisfaction and dissatisfaction identified the cri...

ion", in Proc. of the 1995 IEEE Symp. on Visual Languages, Darmsdart, Germany (Sept. 1995), IEEE CS Press, pp. 53-60. 12. D.Q. Zhang and K.A. Zhang, "Visual Programming Environment for Distributed Systems", in Proc. of the 1995 IEEE Sym. on Visual Languages, Darmsdadt, Germany (Sept. 1995), IEEE CS Press, pp. 310-317. 13. G. Wirtz, "A Visual Approach for Developing, Understanding and Analyzing ...

Autism spectrum disorder (ASD) is mysterious because it involves deficits in social cognition and language, both of which are central to what makes us human. ASD is known to have a strong genetic basis, but little is known about the molecular and neuronal mechanisms. Recent studies identified mutations in hundreds of genes that may contribute to the risk of ASD. We have found that chromatin reg...

Conventional vibrational spectroscopies such as infrared absorption and spontaneous or coherent Raman scattering provide a one-dimensional projection of intermolecular and intramolecular vibrational structure and motions onto a single frequency (or time) axis. For simple molecules with well-separated eigenstates, this gives direct information on energy levels and their oscillator strengths. The...

The synthesis of nanostructured materials with tunable properties is central to developments in nanoscale science and technology. Nonlithographic approaches based on thermodynamically driven self-organization processes are especially appealing because of their potential for low overhead in large-scale production. The spontaneous organization of monolayer-protected metal nanoparticles into perio...

•Single-cell technologies are expanding rapidly, generating novel experimental and analytical methods.•Hitherto unknown rare hematopoietic subpopulations have been identified characterized at the single-cell level.•Single-cell studies reveal heterogeneity, clonal evolution, resistance to therapy in hematological malignancies. In recent years, emerged as breakthrough techniques that enable chara...

The penetration of salt into porous materials is known to have deleterious effects, often resulting in fracture. The damage process begins with a saline solution penetrating the porous network by way of capillary action. This is followed by supersaturation of the saline solution, which may result in the formation of salt crystals. In turn, these salt crystals induce pressure on the pore walls. ...

s | 35 administered at baseline, weeks 1, 2, 4, and week 8.The dose of desvenlafaxine was fixed (50mg/day) until week 4, after which it was flexible up to 100mg/day, based on response and tolerability. Results: Montgomery Asberg Depression Scale scores significantly decreased from baseline (M=23.61, SD=5.51) to end of treatment (M=12.29, SD=8.41), p<.0001. Severity of illness, as measured by th...

s | 35 administered at baseline, weeks 1, 2, 4, and week 8.The dose of desvenlafaxine was fixed (50mg/day) until week 4, after which it was flexible up to 100mg/day, based on response and tolerability. Results: Montgomery Asberg Depression Scale scores significantly decreased from baseline (M=23.61, SD=5.51) to end of treatment (M=12.29, SD=8.41), p<.0001. Severity of illness, as measured by th...

We investigated the effect of adenovirally mediated overexpression of adenylyl cyclase type 6 (AC6), a major form of AC expressed in mammalian heart, on G protein-coupled receptor regulation of cAMP production in neonatal rat ventricular myocytes. Following gene transfer of AC6, isoproterenoland forskolin-stimulated increases in cAMP were markedly enhanced, whereas basal levels of cAMP and resp...