Rapid progress in the field of adult cells reprogramming back into a stem cell-like fate revealed shared mechanisms of action with tumoural reprogramming. A hallmark of stem cells - self-renewal and differentiation potential - seems to be tightly interlaced with large proliferation capacity and cellular plasticity of cancer cells. In this review, we briefly summarise the core transcription fact...

Background and aims: The aim of this study was the modeling of the incidence rates of Colorectal, breast and prostate cancers using a shared component model in order to explore the spatial pattern of their shared risk factors (i.e., obesity and low physical activity) affecting on cancer incidence, and also to estimate the relative weight of these shared components. Methods: In this study,...

[This corrects the article DOI: 10.1371/journal.pbio.1002450.].

Changes in gene expression are thought to be important for morphological evolution, though little is known about the nature or magnitude of the differences. Here, we examine Xenopus laevis and Xenopus tropicalis, two amphibians with very similar development, and ask how their transcriptomes compare. Despite separation for ~30-90 million years, there is strong conservation in gene expression in ...

Objective To understand National Health Service (NHS) staff experiences of working in critical care during the first wave COVID-19 pandemic UK. Design Qualitative study using semistructured telephone interviews and rapid analysis, interpreted Baehr’s sociological lens ‘communities fate’. Participants Forty NHS care, including 21 nurses, 10 doctors advanced practitioners, 4 allied health profess...

Shared psychotic disorder also known as folie a dues is thought to occur in persons who live close together, so that delusions of the primarily ill patient are transferred to the partner. A case of shared paranoid psychotic disorder, with primary diagnosis of persecutory delusional disorder in the husband is described. The delusion and its consequent safety behaviors were so strong that led to ...

the main purpose of this descriptive–survey research was to analysis organizational intelligence components in agricultural organization (jihad-e-keshavrzi) of guilan province. the statistical population of the study consisted of agricultural organization of guilan province’s staffs (n=1296). in order to determine sample size (n=183), the table for determining sample from a given population, de...