the fact that life styles and personal interests, aggregate within families suggests that shared environment in addition to shared bioligical factors could play a role in determining the phenotypic similarity of idividuals living in the same household. it is a major concern of cardiovascular epidemiologists to know how much of the familial aggregation of blood pressure is attributable to shared...

We consider the order fulfillment process of a supplier producing a customized capital good, such as production equipment, commercial aircraft, medical devices, or defense systems. As common in these industries, prior to receiving a firm purchase order from the customer, the supplier receives a series of shared forecasts, which are called ‘soft orders’. Facing a stochastic internal manufacturin...

Background and aims: The aim of this study was the modeling of the incidence rates of Colorectal, breast and prostate cancers using a shared component model in order to explore the spatial pattern of their shared risk factors (i.e., obesity and low physical activity) affecting on cancer incidence, and also to estimate the relative weight of these shared components. Methods: In this study,...

We analyze the benefit of production/service capacity sharing for a set of independent firms. Firms have the choice of either operating their own production/service facilities or investing in a facility that is shared. Facilities are modeled as queueing systems with finite service rates. Firms decide on capacity levels (the service rate) to minimize delay costs and capacity investment costs pos...

Machines at customers have to be provided with spare parts upon failure. Consider a number of groups of machines, for each of which a target aggregate fill rate or target average response time (waiting time) should be met. Between groups, commonality exists, i.e., some parts occur in the material breakdown structure of machines in multiple groups. Instead of using separate stocks per group of m...

This paper compares EPA’s ex ante cost analysis of the 2001 maximum contaminant limit (MCL) for Arsenic in Drinking Water to an ex post assessment of the costs. Because comprehensive cost information for installed treatment technologies or other mitigation strategies pursued by water systems to meet the new standard is not available, this case study relies upon ex post cost data from EPA Demons...

PURPOSE There is debate about the relative merits and costs of private versus shared bedrooms in nursing homes, particularly in light of the current efforts at creating both cost-efficient and person-centered care facilities. The purpose of this project was to explore the extent to which there is evidence-based information that supports the merits of three different bedroom configurations: trad...

In the following we evaluate the costs and beneets of using a cache memory with a decoupled architecture supporting shared memory in both the uniprocessor and multiprocessor cases. Firstly we identify the performance bottleneck of such architectures, which we deene as Loss of Decoupling costs. We show that in both uniprocessors and multiprocessor machines with high latency such costs can greatl...