نتایج جستجو برای: sfas protein

تعداد نتایج: 1235102  

2017
Ju-Sheng Zheng Stephen J Sharp Fumiaki Imamura Albert Koulman Matthias B Schulze Zheng Ye Jules Griffin Marcela Guevara José María Huerta Janine Kröger Ivonne Sluijs Antonio Agudo Aurelio Barricarte Heiner Boeing Sandra Colorado-Yohar Courtney Dow Miren Dorronsoro Pia T Dinesen Guy Fagherazzi Paul W Franks Edith J M Feskens Tilman Kühn Verena Andrea Katzke Timothy J Key Kay-Tee Khaw Maria Santucci de Magistris Francesca Romana Mancini Elena Molina-Portillo Peter M Nilsson Anja Olsen Kim Overvad Domenico Palli Jose Ramón Quirós Olov Rolandsson Fulvio Ricceri Annemieke M W Spijkerman Nadia Slimani Giovanna Tagliabue Anne Tjonneland Rosario Tumino Yvonne T van der Schouw Claudia Langenberg Elio Riboli Nita G Forouhi Nicholas J Wareham

BACKGROUND Accumulating evidence suggests that individual circulating saturated fatty acids (SFAs) are heterogeneous in their associations with cardio-metabolic diseases, but evidence about associations of SFAs with metabolic markers of different pathogenic pathways is limited. We aimed to examine the associations between plasma phospholipid SFAs and the metabolic markers of lipid, hepatic, gly...

Journal: :Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2014
Elena Grasselli Adriana Voci Laura Canesi Annalisa Salis Gianluca Damonte Andrea D Compalati Fernando Goglia Gabriella Gallo Laura Vergani

BACKGROUND/AIMS Fatty acids are the main energy stores and the major membrane components of the cells. In the hepatocyte, fatty acids are esterified to triacylglycerols (TAGs) and stored in lipid droplets (LDs). The lipid lowering action of 3,5-diiodo-L-thyronine (T2) on an in vitro model of hepatosteatosis was investigated in terms of fatty acid and protein content of LDs, lipid oxidation and ...

Journal: :The Southeast Asian journal of tropical medicine and public health 2001
N Chanarat P Chanarat K Viratsethasin M Suttajit D Chiewsilp

HIV/AIDS is a multifactorial and multi-step disease. No single treatment against AIDS can save a patient. Our last report showed that vitamin A, vitamin E and beta-carotene were decreased while malondialdehyde (MDA) was increased. This report aims to evaluate biochemical and hematological parameters in HIV/AIDS patients in Chiang Mai, Thailand by holistic approaches. Sera from HIV/AIDS patients...

2014
Hiroshi Yatsuya Hideaki Toyoshima Koji Tamakoshi Norihiko Hayakawa Kiyomi Sakata Shogo Kikuchi Yoshiharu Hoshiyama Yoshihisa Fujino Tetsuya Mizoue Noritaka Tokui Takesumi Yoshimura

BACKGROUND: The prognosis of stomach cancer with advanced stage remains poor. New biomarkers of the disease that may contribute to establish the potential screening strategy would be of value for the early detection of individuals at high risk of the disease. METHODS: We conducted a prospective, nested case-control analysis among apparently healthy men and women who were followed for up to 8 ye...

ژورنال: :مجله علمی دانشگاه علوم پزشکی قزوین 0
رضا نجفی پور r najafipour قزوین، دانشگاه علوم پزشکی، دانشکده پزشکی، گروه ژنتیک الگا پاولوونا o pavelovna

¯چکیده زمینه: نارسایی قلبی علت اصلی بیماری، ناتوانی و مرگ در تمام کشورهاست که پیش آگهی خوبی ندارد. التهاب و آپوپتوز نقش اساسی درپاتوژنز نارسایی قلبی دارند. fas (cd95)/fasl یکی از فرآیند های تنظیم کننده آپوپتوز است. هدف: مطالعه به منظور تعیین ارتباط سطح نشان گرهای محلول آپوپتوز سیستم /fasl fasدر بیماران با نارسایی قلبی با شدت بیماری انجام شد. مواد و روش ها: این مطالعه مورد- شاهدی در سال های 2004...

Journal: :Mediators of Inflammation 2003
Bozena Dziankowska-Bartkowiak Elzbieta Waszczykowska Anna Zalewska Anna Sysa-Jedrzejowska

Recent studies point out at the role of apoptosis disturbances in the development of systemic sclerosis(SSc). The aim of our study was to examine caspase 1 and sFas serum levels in scleroderma patients and correlate the obtained results with skin involvement and internal organ changes. We studied 29 patients (14 with limited and 15 with diffuse SSc). The extension of skin involvement was measur...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2007
Luis M Blanco-Colio Jose L Martín-Ventura Eduardo de Teresa Csaba Farsang Allan Gaw GianFranco Gensini Lawrence A Leiter Anatoly Langer Pierre Martineau Gonzalo Hérnandez Jesús Egido

OBJECTIVE Increasing evidence indicates that the Fas/Fas ligand interaction is involved in atherogenesis. We sought to analyze soluble Fas (sFas) and soluble Fas ligand (sFasL) concentrations in subjects at high cardiovascular risk and their modulation by atorvastatin treatment. METHODS AND RESULTS ACTFAST was a 12-week, prospective, multicenter, open-label trial which enrolled subjects (stat...

Journal: :GSC Advanced Research and Reviews 2022

Reducing excess dietary saturated fatty acids (SFAs) may be a therapy to slow cognitive decline in vascular dementia (VaD). It has been well established that lower levels of SFAs reduce risk and dementia. In patients who consume high amounts SFAs, limiting intake could improve cognition. Some trials have seen reduction atherosclerotic lesions memory problems with diets reduced total fat. also i...

Abbas Ali Naserian, Mohammad Salmani Izadi, Mohammad Reza Nasiri, Reza Majidzadeh Heravi,

Background: Stearoyl-CoA desaturase (SCD) is a key enzyme that converts saturated fatty acids (SFAs) to monounsaturated fatty acids (MUFAs) in fat biosynthesis. Despite being crucial for interpreting SCDs’ roles across species, the evolutionary relationship of SCD proteins across species has yet to be elucidated. This study aims to present this evolutionary relationship based on amino aci...

ژورنال: :مجله علمی - پژوهشی دانشگاه علوم پزشکی سبزوار 1970
ناهید صدیقی محمدباقر اردشیرلاریجانی ساسان عباس شرقی رامین حشمت پیمان شوشتری زاده

زمینه و هدف: محلول سرمی (sfas)، در افراد سالم به میزان کم وجود دارد و در بیماری های اتوایمیون، بدخیمی ها و بیماری های التهابی افزایش می یابد. این مولکول با مداخله در واکنش fas- fasl در پاتوژنز بیماری گریوز نقش دارد. هدف از این مطالعه ارزیابی ارتباط بین میزان سرمی sfas و اتوآنتی بادی های تیرویید است. مواد و روش ها: در این بررسی برای تعیین ارتباط بین میزان سرمی sfas و اتوآنتی بادی های تیرویید، م...

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