background: hemophilia a and b are the most frequent congenital coagulation disorders. this study was conducted to determine the prevalence of hepatitis b, c and human immunodeficiency viruses among hemophilic patients in hamadan, iran. patients and methods: in this study, patients with hemophilia a and b treated in hamedan hemophilia center, hamedan, iran, were screened for hepatitis b, c and ...

Hemophilia is an inherited bleeding disorder caused by the lack of a protein necessary for blood clotting. Gene therapy hemophilia involves introduction healthy gene into patient's cells to produce missing protein. There are two main types hemophilia: ex vivo therapy, which extraction from patient, these in laboratory, and reintroduction modified patient; direct delivery body using viral vector...

background: factor viii inhibitor is one of the most problems in the treatment of hemophilia. patients with hemophilia who have inhibitors are capable of severe hemorrhage and treatments of these patients are more expensive and more difficult than those patients without inhibitor. the aim of present study was to determine the prevalence of inhibitor and to assess the necessity of screening of t...

Background: Hemophilic children must be thought of as special patients. Although there have been number of studies regarding with oral surgical, periodontal management of hemophilia there is paucity for the dental caries and its severity in hemophiliac children. The objective of this study is to assess prevalence of dental caries and treatment needs among hemophilic children attending Rajasthan...

BACKGROUND AND OBJECTIVES The aim of the study, funded by the Italian Ministry of Health, was to identify the causative mutation in all known patients with hemophilia B in Italy. DESIGN AND METHODS Overall, 269 patients followed by 25 regional centers were considered in the study; after exclusion of the related individuals, 238 unrelated patients were analyzed (153 with severe, 59 with modera...

background: pain, as a crucial subsequence of joint hemorrhages in hemophilia patients, is chronic, debilitating, and distracting. this study aimed to describe and interpret pain experiences of hemophilia patients in their lives. methods: this qualitative study with hermeneutic phenomenological approach was conducted on fourteen hemophilia patients who had been referred to a hemophilia center a...

a group of iranian patients suffering from factor viii deficiency (hemophilia a) and treated with contaminated coagulation factor (imported), became seropositive as determined by elisa method. sixty of these individuals, which were available, were studied for abo distribution. the b blood group in anti hiv pos. individuals (13.33%) shows a significant decrease in comparison with the total (1504...