PURPOSE The purpose of the present study was to investigate the effect of sesame oil on the reproductive parameters of diabetic male Wistar rats. MATERIALS AND METHODS The adult male rats in a split plot design were divided into normal (n=10), normal 5% (n=5; 5% sesame oil enriched diet), diabetic (Streptozocin induced diabetes; n=9), diabetic 5% (n=9; 5% sesame oil enriched diet), and diabet...

BACKGROUND Sesame oil is a potent antioxidant dietary source for human health. Oxidative stress through generation of free radicals damages the myocardium in different experimental condition. The present research was designed to evaluate the antioxidant property of chronic oral administration of sesame oil against isoproterenol induced myocardial injury. METHODS AND RESULTS Male Wistar albino...

Sesame (Sesamum indicum L.) seed and oil have long been used widely as healthy foods to supply energy and prevent aging. Some of the main active anti-oxidative constituents in sesame seeds are γ-tocopherol and phenols. The purpose of this study was to investigate the relationship between roasting temperature and time with γ-tocopherol and total phenolic compounds (TPC) of sesame seeds when roas...

The protective effect of sesamin (SES) from sesame meal on NIT-1 pancreatic β-cells damaged by streptozotocin (STZ) in vitro was investigated. The cell viability, insulin secretion, the activity of superoxide dismutase(SOD), glutathione peroxidase (GSHpx) and the content of reduced glutathione (GSH) increased significantly when incubated with SES (400, 200 µg mL-1). The content of malondialdehy...

Wound healing is a very complex process. Free radicals are generated at the site of injury, which are known to impair the healing process. The use of antioxidants has been shown to promote wound healing. Sesamin and sesamolin are the oil-soluble lignans in the sesame oil extract and proved to have antioxidant activity. In the present study, we have examined the characteristics of sesame oil ext...