Recent epidemiological studies provide a clear evidence that hyperuricemia is associated with hypertension, coronary heart disease, left ventricular hypertrophy and progression of renal disease. Aim of our study was to assess the effect of low dosage of recombinant urate oxidase on hyperuricemia in renal failure patients that already receiving allopurinol. Our study group consisted of 43 renal ...

VARIETY of methods is available for tue colorimetric determination of uric acid. In general, these are based on precipitation of proteins, followed by the reduction in an alkaline medium of phosphotungstate by the uric acid ill the protein-free filtrate. Results of colorimetric determinations may at times vary from “true” uric acid values as determined by unease methods. This is because the col...

Currently serum uric acid is not considered a metabolic biomarker in diabetes. The purpose of the current study was to find the significant associations, correlations and to develop regression models between uric acid, HbA1c, and serum insulin among diabetic patients. The study enrolled type-1 and type-2 diabetic patients for 30 months. For HbA1c and uric acid, patients were divided into two gr...

BACKGROUND The finding reported in a previous paper - alkalization of urine facilitates uric acid excretion - is contradictory to what one might expect to occur: because food materials for the alkalization of urine contain fewer purine bodies than those for acidification, less uric acid in alkaline urine should have been excreted than in acid urine. To make clear what component of uric acid exc...

Background: Pre-eclampsia is a frequent obstetrical problem responsible for adverse effects on pregnancy outcome. Aim: To find role of serum uric as an early predictor o f preeclampsia. Methods: A case control study was conducted on 30 pre-eclampltic women and 20 age matched women with normal pregnancy. Patients were taken from Department of Obstetrics and Gynecology, Sir Ganga Ram Hospital Lah...

The effect of pyrazinamide on serum uric acid and urinary excretion of uric acid was studied in patients with pulmonary tuberculosis. A rise in serum uric acid concentration during drug therapy was associated with a fall in urinary excretion of uric acid. No significant difference was observed between two and three months of drug administration. one out of twenty patients developed arthralgia (...

Serum lipids and serum uric acid have been studied in 50 patients with ischemic thrombotic cerebrovascular disease. Patients having diseases known to predispose to hyperuricemia were excluded. Abnormalities of large vessels were present in 14 or 30 cases (46.6%) as a whole, and in 9 of 16 cases (56.5%) below 40 years of age. Thirty percent of the cases showed hyperuricemia. A statistically sign...

The aim of the study is to review the association between diabetes Mellitus and serum uric acid levels. The objective is to review how uric acid level is related to diabetes Mellitus. Diabetes is an increasingly important disease globally. New data from IDF showed that there are 336 million people with diabetes in 2011 and this is expected to rise to 552 million by 2030. It has been suggested t...

BACKGROUND An elevated serum uric acid level is strongly associated with endothelial dysfunction and inflammation, both of which are common in chronic kidney disease (CKD). We hypothesized that endothelial dysfunction in subjects with CKD would correlate with uric acid levels. MATERIALS AND METHODS We evaluated the association between serum uric acid level and ultrasonographic flow-mediated d...