Serum troponin is a useful laboratory study for the diagnosis of acute myocardial infarction. However, elevations can also be seen in a variety of other diseases processes. Falsely positive troponin values caused by interference with current troponin assays have been reported. We report a unique case that demonstrates the fluctuation of falsely elevated troponin correlating with hemoglobin, ser...

Background: Cardiovascular diseases are the leading cause of mortality worldwide. Therefore, it is important to predict the future consequences of the disease in patients who have recovered. Objectives: We sought to determine the relationship between troponin-I level and 6-month clinical consequences (i.e., re-infarction, death, re-angiography and coronary artery bypass grafting) in patients w...

Background: Cardiovascular diseases are the leading cause of mortality worldwide. Therefore, it is important to predict the future consequences of the disease in patients who have recovered. Objectives: We sought to determine the relationship between troponin-I level and 6-month clinical consequences (i.e., re-infarction, death, re-angiography and coronary artery bypass grafting) in patients w...

inflammatory basis in pathopoiesis of coronary artery disease (cad) have been demonstrated in recent decades. elevated c-reactive protein (crp) and leukocytosis were associated with an elevated risk   for acute coronary syndrome (acs). to evaluate the relationship between quantitative crp and cardiac troponin i in conjunction with white blood cell (wbc) count and 30 days outcomes and treatment ...

Objective(s):Biochemical markers are important for the timely diagnosis and follow-up of ischemic events. Most of the markers have been previously studied in the context of cardiac ischemia. However, research on markers of non-cardiac events has been insufficient. Therefore, we investigated the relationship between troponin and myoglobin which are commonly used markers of cardiac ischemia, in n...

1 Roongsritong C, Warraich I, Bradley C. Common causes of troponin elevations in the absence of acute myocardial infarction: incidence and clinical significance. Chest 2004; 125: 1877–1884 2 Kumar A, Thota V, Dee L, et al. Tumor necrosis factor and interleukin 1 are responsible for in vitro myocardial cell depression induced by human septic shock serum. J Exp Med 1996; 183:949–958 3 van Bockel ...

The intramolecular fluorescence self-quenching phenomenon is a major drawback in developing high-performance fluorometric biosensors which use common fluorophores as signal generators. We propose two strategies involving liberation of the fluorescent molecules by means of enzymatic fragmentation of protein or dehybridization of double-stranded DNA. In the former, bovine serum albumin (BSA) was ...

The RCPAQAP provides a Liquid Serum Chemistry Program sourced from consenting male and female haemochromatosis patients presenting for therapeutic venesection. Where possible, serum individual are pooled over successive collections. option to report Troponin I T was introduced in the 2022 program. We sought review performance at low levels across 10 instruments five vendors, four Roche instrume...