BACKGROUND Schizophrenia is a prevalent neurodevelopmental disorder of an unknown etiology and a variable phenotypic expression. In the recent years, the impact of hormones on the course of schizophrenia has been investigated. This study is aimed at assessing the level of correlating serum levels of hormones in schizophrenic male patients with their cognitive functioning measured with neuropsyc...

results there was a significant increase (p < 0.05) in leptin levels on day 14 (12.75 + 5.8 ng/ml) and day 21 (12.91 + 3.2 ng/ml) for age group 18-30 years compared to day 14 (11.60 + 3.2 ng/ml) and day 21 (11.60 + 3.2 ng/ml) for age group 31-40 years. leptin was positively correlated with fsh on day 14, with lh on day 7 and day 21; likewise, with progesterone on day 21 and day 28 and with estr...

Growth differentiation factor-8 (GDF-8) is found in the human serum, follicular fluid and granulosa cells. Our previous studies have shown that the human cumulus expansion and steroidogenesis can be regulated by GDF-8. However, thus far, the expression profile of GDF-8 in serum and whether the level of serum GDF-8 influences pregnancy results for patients treated with in vitro fertilization/int...

Background The aim of this study was to evaluate the relationship between ultrasonographic findings and serum progesterone and cancer antigen-125 (CA-125) levels in threatened miscarriage and to predict pregnancy outcome. MaterialsAndMethods In a prospective comparative case-control study, serum CA-125 and progesterone levels were measured for 100 pregnant women with threatened miscarriage who ...

background: aqueous extract of winter cherry ( physalis alkekengi l; family of solanaceae) fruits (wcf) has long been recommended for fertility control by herbalists in iran. the effect of this extract on lowering serum progesterone levels has been reported previously.   objective: to study the effects of wcf extract on the activities of ovarian 3β-hydroxysteroid dehydrogenase (3β-hsd) responsi...

In order to throw further light on the role of androgens in the aetiology of the polycystic ovary syndrome (PCO) we have examined the effect of artificially increasing serum testosterone levels on menstrual function in a group of ovulating women. Six women were studied who had either severe premenstrual syndrome or loss of libido for which they were treated with 100 mg testosterone by s.c. impl...

migraine is one of the common varieties of headache. it involves 4 to 6 percent of men and 13 to 16 percent of women under 30 years in more than 80% of cases. some studies have shown that in 50% of patients serum magnesium level decreases during attacks of headache and using magnesium tablets and intravenous magnesium sulfate is more effective for treatment of migraine attack, than placebo. thi...

Our objective was to investigate the first-pass effect to the uterus of progesterone gel administered vaginally. This was a prospective, randomized study of 32 postmenopausal women, attending our menopause clinic. All women used transdermal estradiol (50 microg/day, a patch each week) for 2 weeks. They used either vaginal progesterone gel or intramuscular progesterone in oil 50 mg after 24 h to...

We describe a simple, solid-phase chemiluminescence immunoassay for progesterone in 10 microL of unextracted serum ("direct" assay). Danazol at pH 8.0 is included (100 ng per tube) to displace progesterone from binding proteins in serum. A progesterone-11 alpha-hemisuccinyl-aminobutylethyl isoluminol conjugate serves as the chemiluminescent ligand marker and homologous antiprogesterone IgG cova...