objective(s): visfatin and vaspin are secreted by adipose tissue and play key roles in glucose homeostasis and subsequently are potential targets for diabetes treatment. resveratrol (rvs) corrects insulin secretion and improves insulin sensitivity. we investigated the rvs effects on serum antioxidants, insulin and glucose levels, also visfatin and vaspin genes expression in adipose tissue of st...

Background: Sickle cell disease (SCD) which is characterized by abnormal hemoglobin structure has a carrier rate of 9-20% in Egypt. Reactive oxygen species (ROC) in SCD cause multiple organ injuries, endocrine complications and metabolic alteration such as insulin resistance (IR) in children and young adults. We aimed to determine the presence of IR in normoglycemic SCD patients and also assess...

SUMMARY OBJECTIVE: Polycystic ovary syndrome can be divided into different subtypes, including insulin resistance and hyperandrogenism. The aim of this study was to investigate the relationship between serum asprosin levels polycystic subtypes. METHODS: A total 93 women with 77 healthy as controls were selected for study. clinical laboratory data compared group control group. further subgroups:...

Acanthosis nigricans (AN) refers to the velvety, black hyperpigmentation in flexures usually on neck and axillae. AN is associated with multiple endocrinopathies insulin resistance reported be a common denominator among them. The aim of study was identify correlation metabolic factors (Serum glucose, lipid profile), endocrine (TSH, serum insulin), nutritional (vitamin B12, Ferritin) patients Ar...

gestational diabetes mellitus (gdm) is one of the important problems in pregnant women. this study conducted to determine association the level of serum glucose with fetal-maternal complications of gestational diabetes with insulin therapy. this study has been conducted as an existing data study, so medical records of all pregnant women with gdm that have been treated with insulin during 2 year...

background: pomegranate seed oil and its main constituent, punicic acid, have been shown to decrease plasma glucose and have antioxidant activity. the objective of the present study was to examine the effects of pomegranate seed oil on rats with type 2 diabetes mellitus. method: six groups (n=8 each) of male sprague-dawley rats, comprising a control, a diabetic (induced by streptozocin and nico...