نتایج جستجو برای: serum ige

تعداد نتایج: 315897  

Journal: :Annals of the rheumatic diseases 1976
D L Conn G J Gleich R A DeRemee T J McDonald

Five patients with Wegner's granulomatosis were found to have significantly raised serum immunoglobulin E (IgE) levels. The rise in IgE was not related to the extent of clinical involvement, was not part of a generalized serum immunoglobulin rise, and was not associated with eosinophilia. Raised serum IgE may be a clue to the pathogenesis of this disease.

2013
H. BUCKLEY SUSANA. Fiscus

seen in hypogammaglobulinemic patients. Group mean IgD concentrations were also depressed in patients with Wiskott-Aldrich syndrome and in those with selective IgA deficiency; IgE concentrations were depressed in patients with X-linked immunodeficiency with hyperIgM and in those with ataxia telangiectasia. IgD and IgE were both significantly elevated in patients with extreme hyperimmunoglobulin...

2016
Jeffrey M. Harris Romeo Maciuca Mary S. Bradley Christopher R. Cabanski Heleen Scheerens Jeremy Lim Fang Cai Mona Kishnani X. Charlene Liao Divya Samineni Rui Zhu Colette Cochran Weily Soong Joseph D. Diaz Patrick Perin Miguel Tsukayama Dimo Dimov Ioana Agache Steven G. Kelsen

BACKGROUND Quilizumab, a humanized IgG1 monoclonal antibody, targets the M1-prime segment of membrane-expressed IgE, leading to depletion of IgE-switched and memory B cells. In patients with mild asthma, quilizumab reduced serum IgE and attenuated the early and late asthmatic reaction following whole lung allergen challenge. This study evaluated the efficacy and safety of quilizumab in adults w...

2016
Tae Keun Yoo Sun Woong Kim Kyoung Yul Seo

BACKGROUND Previous research has suggested that immunoglobulin E (IgE)-mediated events lead to several chronic diseases. We investigated the association between allergic conditions and age-related cataracts in the South Korean adult population. METHODS A cross-sectional study was performed using data obtained from 1,170 participants aged 40 years or older who were enrolled in the Korean Natio...

Journal: :Circulation 1988
A Szczeklik K Sladek A Szczerba J Dropinski

Mast cells have been implicated in the pathogenesis of coronary heart disease. They can be activated by immunoglobulin (Ig) E-mediated mechanisms to release powerful mediators affecting local blood flow. We have determined systematically serum IgE concentrations in 100 patients with acute myocardial infarction. There was a consistent pattern of change in serum IgE, characterized by a significan...

Journal: :International journal of dermatology 1976
H E Jones T R Wade

Coca and Grove (1925) concluded that serum factors, which they called reagins, were present in individuals with allergic respiratory disease. More than 40 years later, reaginic antibody was shown by Johansson and Ichizaka to belong to the immunoglobin E (IgE) class of immunoglobins. It has been established that the Fc component of IgE has an affinity for surface receptors on mast cells and baso...

2012
Ravi Babu Kalahasthi HR Rajmohan Pavitra Narendranan Adithya Pradyumna

BACKGROUND The exposures of bio-aerosols have reported higher occupational health hazards, the association between serum total IgE levels and job categories and occupational health hazards of waste disposal area was limited. The present study was undertaken to assess the relationship between occupational health hazards and Serum total IgE in waste disposal area. MATERIALS AND METHODS One hund...

Journal: :American journal of veterinary research 1997
D D Collie D J DeBoer B A Muggenburg D E Bice

OBJECTIVE To characterize the relation between bronchoalveolar and blood eosinophil numbers, serum total IgE concentration, and nonspecific airway reactivity in healthy dogs. ANIMALS 26 healthy Beagles. PROCEDURE Prior to measurement of nonspecific airway responsiveness, dogs were anesthetized and bronchoscopy was performed to recover bronchoalveolar lavage (BAL) fluid. Repeated measurement...

Journal: :iranian journal of medical sciences 0
g.a. kardar z. pourpak g. jafarzadeh fard m.r. eshraghian s. shams

determining the normal range of immunoglobulin e (ige) in any population is important for diagnosis of allergic diseases. the aim of this study was to determine normal values of ige in children living in tehran. two-handed and fifty six healthy children aged one month to 14 years were selected. these children had neither parasitic infections nor atopic disease. they were divided into six groups...

Journal: :The Israel Medical Association journal : IMAJ 2005
Mona Iancovici Kidon Miguel Stein Carmi Geller-Bernstein Ziva Weisman Shoshana Steinberg Zalman Greenberg Zeev T Handzel Zvi Bentwich

BACKGROUND Since 1984, several waves of Ethiopian immigrants have settled in Israel. On arrival they were found to be highly infected with intestinal parasites and to have increased serum immunoglobulin E and eosinophilia. OBJECTIVES To study serum IgE levels in Ethiopian children growing up in the environment of Israel. METHODS We assessed four groups of children of Ethiopian origin: a) ad...

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