BACKGROUND Serum follicle stimulating hormone (FSH) levels are used clinically to evaluate infertility, pituitary and gonadal disorders. With increased frequency of research collaborations across institutions, it is essential that inter-laboratory validation is addressed. METHODS An inter-laboratory validation of three commercial FSH immunoassays was performed with human serum samples of vary...

Follicle-stimulating hormone (FSH) in the organism together with LH is responsible for follicular growth and maturation of eggs. If the ovaries are not working, FSH levels rise. The most common reason for high serum FSH concentration is in a female who is undergoing or has recently undergone menopause. High levels of follicle-stimulating hormone indicate that the normal restricting feedback fro...

background: anti-müllerian hormone (amh) is secreted by the granulosa cells of growing follicles during the primary to large antral follicle stages. abnormal levels of amh and follicle stimulating hormone (fsh) may indicate a woman’s diminished ability or inability to conceive. our aim is to investigate the changes in serum amh and fsh concentrations at different age groups and its correlation ...

OBJECTIVES The aim of this study was to determine day 3 Serum AMH, FSH, LH, Estradiol (E2), Inhibin B levels, ovarian volume, and antral follicular count to assess ovarian function. METHODS This study was conducted on 130 infertile women between age 18 and 43 years. Day 3 Serum AMH level was estimated by sandwich enzyme immunoassay; Serum FSH, S. LH, S. E2, by solid-phase two-site chemilumine...

Polydimethylsiloxane (Silastic) capsules containing crystalline testosterone were implanted subcutaneously in castrate lambs and evaluated for their ability to (1) provide stable, physiological concentrations of serum testosterone and (2) regulate secretion of LH and FSH. Testosterone was nondectable (< .2 ng/ml) between 12 and 24 weeks of age in the serum of castrate lambs implanted with empty...

The effects of the gonadotrophin-releasing hormone, synthetic decapeptide luteinizing hormone/follicle stimulating hormone-releasing hormone (LH/FSH-RH), have been studied in 18 normal men and five women in the follicular phase of their menstrual cycle. Rapid and dose-dependent (25 to 100 mug) increases in serum immunoreactive LH were seen, which reached a peak 20 to 30 minutes after a rapid in...

OBJECTIVE To assess the pharmacogenetic potential of FSH for infertility treatment. DESIGN Review of the literature and genomic databases. METHODS Single-nucleotide polymorphism (SNP) assessed: rs6166 (c.2039A>G, p.N680S), rs6165 (c.919A>G, p.T307A), rs1394205 (c.-29G>A) in FSHR, and rs10835638 (c.-211G>T) in FSHB. Literature search via PubMed. Blast analysis of genomic information availabl...

Fragile X premutations are known to be a risk factor for diminished ovarian function at a relatively young age. We studied endocrine profiles of female fragile X family members (n = 79) at risk of premature ovarian failure (POF). Of these 79 women aged <40 years, 45 had menstrual cycles, and 34 were using oral contraceptives. Of the women with menstrual cycles, the premutation carriers had high...

In this study, serum FSH (follicle stimulating hormone) concentrations of prepubertal 48 female Norduz lambs born in Sheep Farm of Agricultural Faculty of Yüzüncü Yıl University were determined. Lambs were born in February, and within a month. After the parturition, live weights of ewes and lambs were recorded. The lambs were kept with their dams for three months. The lambs were fed adlibitum b...

SUMMARY Concentrations of luteinizing hormone (LH) and follicle stimulating hormone (FSH) were determined in serum of crossbred beef bulls during pubertal development. Serum LH ranged between .5 and 2.0 ng/ml with highest concentrations observed as 12 months of age. Serum FSH varied considerably among individuals but mean concentrations were within the normal range (50 to 100 ng/ml). Neither LH...