Key words: acute renal failure; interstitial nephritis; elevated serum total protein, together with a slight MHC class II antigen; tubular basement membrane decrease in serum albumin was noted. Serum creatinine immune deposition was 3.6 mg/dl and blood urea nitrogen was 53 mg/dl. Serum chloride was slightly increased (112 mmol/l). The endogenous creatinine clearance was 21.6 ml/min/ 1.73 m2. Se...

The mechanism by which excessive sodium chloride intake raises blood pressure has not been fully clarified. The present study was therefore undertaken in patients with essential hypertension to investigate the possible role of an intracellular calcium-dependent mechanism in salt sensitivity. The difference in mean blood pressure between a week of low sodium chloride diet (3 g/day) and a week of...

Ž . Growth rates of rainbow trout Oncorhynchus mykiss were assessed with respect to serum concentrations of cortisol, glucose, and chloride following exposure to a standardized handling Ž . stressor. Individually tagged rainbow trout Ns400, 90–250 g were reared for 10 months and the handling stressor was administered three times at approximately 3-month intervals. Fish were bled at either 1-, 3...

The combination of an increased serum total co2 content and lowered levels of serum chloride may result from a primary retention of co2 as in cardiopulmonary disease with a secondary lowering of the chloride level, referred to as respiratory acidosis, or it may represent one of the two forms of metabolic alkalosis, i.e., the hypochloremic type stemming from losses of extracellular chloride rath...

The chemiluminescence (CL) intensities of various indole derivatives substituted with a glyoxylyl group at the 3-position and a hydroxyl group at the 5-position of the indole ring were compared upon the addition of H2O2 in alkaline media. The CL intensities of 3-indoleglyoxylyl chloride, 3-indoleglyoxylic acid, 5-hydroxyindole and 5-benzyloxyindole in CH3CN were 5.9-, 48-, 5.9- and 3.3-fold str...

BACKGROUND Metabolic acidosis is highly prevalent in critically ill patients with acute renal failure. Little is known about the mechanisms by which renal replacement therapy intervenes in such cases. The objective of this study is to analyze the role of hemodialysis in acidosis correction in intensive care unit patients, with an emphasis on chloride levels in plasma and dialysate. METHODS We...

INTRODUCTION Acetazolamide is commonly given to chronic obstructive pulmonary disease (COPD) patients with metabolic alkalosis. Little is known of the pharmacodynamics of acetazolamide in the critically ill. We undertook the pharmacodynamic modeling of bicarbonate response to acetazolamide in COPD patients under mechanical ventilation. METHODS This observational, retrospective study included ...

An improved microprocedure for the determination of tocopherol in blood serum is reported. Tocopherol is oxidized by ferric chloride and the pink complex of ferrous ions with 4,7-diphenyl10,10-phenanthroline (bathophenanthroline) is determined spectrophotometrically. The test is more sensitive than colorimetric methods using 2,2’,2” -tripyridine,2,2’-bipyridine (bipyridyl) or 2,4,6tripyridyl-s-...

Nonspecific inhibitors of rubella hemagglutination can be removed by treatment of sera with heparin-manganous chloride for use in the hemagglutination-inhibition test. After removal of nonspecific inhibitors by this procedure, an excess of manganous chloride may remain. This may cause the cells to agglutinate, thus obscuring the reading at low serum dilutions. This disadvantage can be overcome ...

An ion exchange-gravimetric method, previously developed as a National Committee for Clinical Laboratory Standards (NCCLS) reference method for the determination of sodium in human serum, has been re-evaluated and improved. Sources of analytical error in this method have been examined more critically and the overall uncertainties decreased. Additionally, greater accuracy and repeatability have ...