Injectable Hydrogels In article number 2101284 by Chien-Chi Lin and co-workers, a biocompatible pH/thermo dual responsive injectable hydrogel is synthesized reversible addition-fragmentation chain-transfer (RAFT) polymerization acylhdrazone click chemistry. Upon injection, sol-gel transition occurs rapidly at body temperature the porous hydrogels degrade slowly under mild acidic condition due t...

Bovine and human serum albumin (BSA and HSA) are globular proteins that function as bloodstream carriers of hydrophobes such as fatty acids and drugs. We fabricated novel photonic crystal protein hydrogels by attaching 2D colloidal arrays onto pure BSA and HSA hydrogels. The wavelengths of the diffracted light sensitively report on the protein hydrogel surface area. The binding of charged speci...

The present study is aimed at developing novel type of interpenetrating polymeric network (IPN) hydrogels of chitosan with poly(acrylic acid) for the controlled release of amphetamine drug. IPN hydrogels were synthesized by simultaneous polymerization/crosslinking of acrylic acid monomer in the presence of chitosan and crosslinker. The swelling properties and in vitro drug release characteristi...

New semi-interpenetrating polymeric network (IPN) hydrogels based on chitosan and poly(acrylic acid), crosslinked with glutaraldehyde, were prepared by free radical polymerization method. IPN hydrogels were synthesized by simultaneous polymerization/crosslinking of acrylic acid monomer in the presence of chitosan and crosslinker. The structure and surface morphology of the IPN hydrogels were ch...

A new type of biosensor is proposed that combines the recognition properties of "intelligent" hydrogels with the sensitivity and reliability of microfabricated pressure transducers. In the proposed device, analyte-induced changes in the osmotic swelling pressure of an environmentally responsive hydrogel are measured by confining it within a small implantable enclosure between a rigid semipermea...

A novel thermo-sensitive superabsorbent hydrogel with saltand pH-responsiveness properties was obtained by grafting of mixtures of acrylic acid (AA) and N-isopropylacrylamide (NIPAM) monomers onto kappa-carrageenan, kC, using ammonium persulfate (APS) as a free radical initiator in the presence of methylene bisacrylamide (MBA) as a crosslinker. Infrared spectroscopy was carried out to confirm t...

Hydrogels of an interpenetrating polymeric network (IPN) composed of the temperaturesensitive poly(N-isopropylacrylamide) (PNIPAAm) and the pH-sensitive poly(methacrylic acid) (PMAA) were prepared by a sequential UV polymerization method. The IPN hydrogels were characterized for their temperatureand pH-responsive behavior by equilibrium swelling studies, oscillatory swelling studies, and differ...

Hydrogels are macromolecular networks able to absorb and release water solutions in a reversible manner, in response to specific environmental stimuli. Such stimuli-sensitive behaviour makes hydrogels appealing for the design of ‘smart’ devices, applicable in a variety of technological fields. In particular, in cases where either ecological or biocompatibility issues are concerned, the biodegra...