Cassia angustifolia Vahl. (Senna), is a versatile medicinal plant that enjoys considerable reputation in Ayurveda, Unani and Allopathic medicine system worldwide. It contains sennosides (2.5% the leaves 3.6% pods), which are utilized to treat habitual constipation other related problems. Senna cultivation done successfully India; however, primary post-harvest processing techniques not optimized...

A 58-year-old man with a history of hemorrhoidectomy and chronic constipation presented for routine surveillance colonoscopy. He took an over-the-counter herbal laxative containing senna for constipation. The rectal mucosa showed a brownish discoloration in a moire pattern, characteristic of melanosis coli. Advancing beyond the rectum, the full circumference of colonic mucosa turned jet black i...

Sub-acute Toxicity of Aqueous Extracts of Tephrosia vogelii, Vernonia amygdalina and Senna occidentalis in Rats Immaculate Nabukenya1*, Chris Rubaire-Akiiki1, Denis Mugizi1, John Kateregga1, Deogracious Olila1 and Johan Höglund2 1College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, P.O. Box 7062, Kampala, Uganda 2Department of Biomedical Sciences and Veterinary...

Laxative drugs are usually organized according to their mode of action, i.e. bulk forming agents, stool softeners, lubricants, saline laxatives, stimulants including some combined formulations. Among them, bulk forming laxatives promote the mildest laxation. The popular bulk forming herbal laxatives in Thailand and Southeast Asian countries are dry fruits of hairy basil (Ocimum americanum) and ...

In semi-arid regions, trees often wither during the dry season. Withering is sometimes manifest as die-back, whereby whithering results in shoot death, which progresses downward from the uppermost part of the crown. In this study, we measured the relationships between height growth and diameter at breast height, die-back frequency and severity, vessel size and specific hydraulic conductivity of...

Several poly-herbal formulations containing senna (Cassia angustifolia) leaves are available in the Indian market for the treatment of constipation. The purgative effect of senna is due to the presence of two unique hydroxy anthracene glycosides sennosides A and B. A HPTLC method for the quantitative analysis of sennosides A and B present in the formulation has been developed. Methanol extract ...