The aim of this study is to explore the effect of Tinospora cordifolia (Guduchi) on cardiotoxicity in streptozotocin induced diabetic rats. All animals were divided into 8 groups of 5 animals each, fed with High fat diet (HFD) except the ones in Sham, NPD and NPD-C-I groups. Food and water intake were monitored daily at the same time during the experimental period. The Food Efficiency Ratio (FE...

*Corresponding author: Dr. Jaimala sharma, Department of Zoology, University of Rajasthan, Jaipur-302055, India. E-mail: [email protected] Background: Radiotherapy is the main modality of cancer treatment. There are many chemical radioprotectors which unfortunately have lethal or toxic effect. Therefore the search is on to find out natural plant based radioprotectors. A well known medi...

The present study was carried out to investigate the antidyslipidemic activity of Tinospora cordifolia stem extract in alloxan-induced (150 mg/kg body wt.) diabetic rats. There was significant increase in plasma markers of diabeticdyslipidemia namely: the levels of glucose, glycosylated hemoglobin(HbA1c) lipid peroxide, total lipid and free fatty acids (FFA).The abnormalities with lipid metabol...

Tinospora cordifolia (RTc) has already been reported to protect whole-body lethally irradiated mice. This study has focussed on certain aspects of immuno-competence, which are adversely affected by irradiation. This study included estimation of spleen size, cell count, DNA fragmentation and apoptosis in splenocytes. The adherence, spreading and phagocytic activities of macrophages were also ass...

Guduchi also known as having heart shaped leaves, belongs to family Menispermaceae native Indian subcontinent. The aqueous and methanol stem extract of is being used for their Immunomodulatory activity they revive immune imbalance which helps in preventing healing many diseases. intensively studied its immunomodulating effects because wide-ranging uses treating diseases related system indigenou...

Depression is a complex psychiatric disorder characterized by depressed mood, anhedonia, loss of energy and low self esteem. Nitric oxide (NO) is the smallest biologically active molecules which plays an important role in the intracellular signaling. NO negatively controls the levels of 5-HT. Inhibition of NO synthases (NOS) which are responsible for the production of NO; may exert antidepressa...

In this study, the RAPD (Random Amplified Polymorphic DNA) technique was employed for determination of the components in an Ayurvedic herbal prescription, Rasayana Churna. One-hundred-and-twenty decamer oligonucleotide primers were screened in the RAPD analysis to identify three Ayurvedic medicines, dried stem of Tinospora cordifolia, dried fruit of Emblica officinalis and dried fruit of Tribul...