Author Affiliations: 1Department of Internal Medicine, Second Faculty of Medicine, Charles University, Prague, Czech Republic; 2Outpatient Department of Diabetology, Internal Medicine and Metabolism, Košice, Slovakia; 3Institute of Computer Science, Academy of Sciences of the Czech Republic, Prague, Czech Republic; and 4Centre for Diabetes, Metabolism, and Nutrition Research, Third Faculty of M...

1 Institute of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha 410011, China 2Center for Stem Cell and Tissue Engineering, School of Medicine, Zhejiang University, Hangzhou 310058, China 3Department of Clinical Cell Biology, Vejle Hospital-Lillebaelt Hospital, Institute of Regional Health Science, University of Southern Denmark, 7100 Vejle, Denmark ...

A new hallmark of cancer involves acquisition of a lipogenic phenotype which promotes tumorigenesis. Little is known about lipid metabolism in melanomas. Therefore, we used BRB (Biometrics Research Branch) class comparison tool with multivariate analysis to identify differentially expressed genes in human cutaneous melanomas, compared with benign nevi and normal skin derived from the microarray...

The traditional method for sparkling wine making consists of a second fermentation base followed by ageing in the same bottle that reaches consumers. Nitrogen metabolism is most important process after carbon and takes place during yeast. Amino acids are numerous nitrogen compounds released this process. They contribute to organoleptic properties wines and, therefore, their sensory quality. mai...

effect of zinc cyanide on protein and certain metabolites content and some enzymes activitieswas evaluated in liver, muscle and gill tissues of the freshwater fish, cirrhinus mrigala, during exposure andfollowing cessation of exposure. fish exhibited significant alterations in the biochemical parameters in alltissues studied. levels of total protein decreased in all tissues, where as free amino...

effect of different co2 concentrations on sucrose metabolizing enzymes and on carbohydrate metabolism was studied for eight blackgram (vigna mungo l. hepper) genotypes grown in open top chambers under ambient (380 µmol mol-1) vs. elevated co2 (550 and 700 µmol mol-1) levels. the higher acid invertase activity over neutral invertase indicated the major role of acid invertase in sucrose breakdown...

introduction biotinidase deficiency is a life threatening inborn error of metabolism specially when delayed in diagnosis. we report a 2-month-old male infant that presented with refractory infantile spasm, alopecia and seborrheic dermatitis. with a high suspicion of the biotinidase deficiency we started biotin 10 mg daily orally before definite diagnosis was made. rapid treatment was life-savin...

helicobacter hepaticus was discovered in 1992 as a cause of liver cancer in the a/jcr mouse model. in susceptible mice, infection by h. hepaticus causes chronic gastrointestinal inflammation leading to neoplasia. it can also cause morphological changes in breast-glands leading to neoplasm and adenocarcinoma in mouse models. studies performed on humans have revealed that h. hepaticus may also be...

Chemically active droplets provide simple models for cell-like systems that can grow and divide. Such droplet are driven away from thermodynamic equilibrium turn over chemically, which corresponds to a metabolism. We consider two scenarios of non-equilibrium driving. First, via the system boundaries by external reservoirs supply nutrient remove waste (boundary-driven). Second, chemical energy p...

Following formative work in the 1970s, disappearance in the 1980s, and reemergence in the 1990s, a chronological review shows that the past decade has witnessed increasing interest in the study of urban metabolism. The review finds that there are two related, non-conflicting, schools of urban metabolism: one following Odum describes metabolism in terms of energy equivalents; while the second mo...