Sebaceous glands (SGs) undergo cyclic renewal independent of hair follicle stem cells (HFSCs) activation while HFSCs have the potential to differentiate into sebaceous gland cells, hair follicle and epidermal keratinocytes. Abnormalities of sebaceous gland progenitor cells contribute to the development of sebaceous neoplasms, but little is known about the role of HFSCs during sebaceous neoplasm...

Syringocystadenoma papilliferum is an uncommon benign apocrine gland tumour, mostly of congenital or early childhood onset, affecting head and neck. In addition, nevus sebaceous is commonly associated with this tumor. Here, we document three cases of syringocystadenoma papilliferum with many atypical features, such as the involvement of rare sites (abdomen, axilla and thigh), absence of nevus s...

adnexal tumors (ats) are primary skin tumors with benign or rarely, malignant behavior. they have been classified based on differentiation towards hair follicle, sebaceous, apocrine or eccrine gland. few large-scale studies have focused on ats. to determine the prevalence of ats and to assess clinical and histopathological trend of ats. a retrospective descriptive study of all ats diagnosed in ...

Sebaceous glands perform complex functions, and they are centrally involved in the pathogenesis of acne vulgaris. Current techniques for studying sebaceous glands are mostly static in nature, whereas the gland's main function-excretion of sebum via the holocrine mechanism-can only be evaluated over time. We present a longitudinal, real-time alternative-the in vivo, label-free imaging of sebaceo...

Sebaceous lymphadenoma is an unusual salivary gland neoplasm which is rarely correctly diagnosed pre-operatively in the parotid gland. Two cases of sebaceous lymphadenoma are presented in which, in common with most cases reported in the literature, the correct pre-operative diagnosis was not made. Sebaceous lymphadenoma rarely transforms into a malignant tumour. Fine needle aspiration cytology ...

BACKGROUND: Sebaceous lymphadenoma is a rare benign salivary gland tumour of uncertain histogenesis. So is synchronous occurrence of two benign or malignant neoplasms. CASE-REPORT: 68-year-old female presented with right side parotid swelling associated with pain and gradual increase is size. Fine needle aspiration cytology of parotid swelling was suggestive of pleomorphic adenoma. Total conser...

The sebaceous gland is composed of sebaceous gland cells that accumulate intracellular lipid droplets when undergoing differentiation. The extent of lipid droplet formation within the sebaceous gland cells thus represents their differentiation status. On reaching maturity, the sebaceous gland cells are then destroyed and the intracellular lipids are secreted to the skin surface whereby they for...

At their ¢rst studies on the physiology and pathophysiology of the skin looking for an adequate ¢eld of future dedication, budding skin researchers usually go quickly through the chapter on the Biology of Sebaceous Glands having obtained the following piece of knowledge: sebaceous glands produce sebum and are partially responsible for acne vulgaris. Seemingly, a limited and less attractive ¢eld...