نتایج جستجو برای: sebaceous differentiation

تعداد نتایج: 230160  

2017
Kanwalpreet Kaur Karuna Gupta Deepika Hemrajani Ajay Yadav Kalpana Mangal

BACKGROUND Skin adnexal tumors (SAT) encompass wide spectrum of benign and malignant tumors that differentiate toward one or more adnexal structures found in normal skin. Overall incidence of SATs is low yet they can be challenging to diagnose. AIMS The aim of this study is to study the spectrum and microscopic features of SATs. MATERIALS AND METHODS It was a retrospective cross-sectional, ...

Journal: :Development 2004
Cristina Lo Celso David M Prowse Fiona M Watt

When beta-catenin signalling is disturbed from mid-gestation onwards lineage commitment is profoundly altered in postnatal mouse epidermis. We have investigated whether adult epidermis has the capacity for beta-catenin-induced lineage conversion without prior embryonic priming. We fused N-terminally truncated, stabilised beta-catenin to the ligand-binding domain of a mutant oestrogen receptor (...

Journal: :Acta dermato-venereologica 1998
J Kanitakis I al-Rifai M Faure A Claudy

The Thomsen-Friedenreich (T) antigen is the core disaccharide of cancer-associated carbohydrates, whose expression allegedly correlates with the prognosis of some carcinomas. We studied the expression of the T antigen and its precursor (Tn) with monoclonal antibodies in formalin-fixed specimens of normal skin and various benign cutaneous tumours and inflammatory lesions (n: 105). In normal skin...

Journal: :The American Journal of dermatopathology 2006
Erik S Cabral Aaron Auerbach J Keith Killian Terry L Barrett David S Cassarino

Sebaceous lesions, including sebaceous hyperplasia, sebaceomas, and sebaceous adenomas and carcinomas, are histologically distinctive adnexal proliferations with a spectrum of biological behavior ranging from benign to frankly malignant. The histologic distinction between sebaceous adenomas and carcinomas may be challenging, especially in cases showing atypical features and in small or partial ...

Journal: :Experimental dermatology 2004
Christos C Zouboulis Markus Böhm

A causative link between emotional stress and acne has long been postulated. There is mounting evidence that the molecular mechanism underlying this observation is related to the expression of receptors for several neuroendocrine mediators by the sebaceous gland. Recent and ongoing studies have indicated that human sebocytes express functional receptors for corticotropin-releasing hormone, mela...

Journal: :Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2008
Irving Dardick M Jane Thomas

For classification purposes, proper identification of infrequent and unique salivary gland tumors requires the gradual accumulation of a sufficient number of cases. Lymphadenoma (i.e., an adenomatous, generally parotid-based lesion with an exaggerated lymphocytic infiltrate, but a lack of sebaceous differentiation) has approximately 9 reported cases. This report adds 2 additional cases occurrin...

Journal: :Actas dermo-sifiliograficas 2018
C Bernárdez L Requena

Malignant cutaneous adnexal neoplasms form a group of rare, typically low-grade-malignancy carcinomas with follicular, sebaceous, apocrine, or eccrine differentiation or a combination of the first 3 subtypes. Their clinical presentation is usually unremarkable, and biopsy is required to establish the differentiation subtype and the definitive diagnosis. Due to their rarity, no clear consensus h...

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