The dried root of Baikal skullcap (Scutellaria baicalensis) has been historically and widely used in traditional Eastern medicine. Modern science proved that baicalin is the major bioactive responsible for the physiological activity of Baikal skullcap. Baicalin, a flavonoid found in several species in the genus Scutellaria, has been regarded as a potent anticancer agent. In this review, we pres...

The Scutellaria species (Lamiaceae) is used as a source of flavonoids to treat a variety of diseases in traditional medicine. In spite of many reports about the cytotoxic and antitumor effects of some species of this genus, anticancer researches on one of the Iranian species S. litwinowii have not yet been conducted. The cytotoxic properties of total methanol extract of S. litwinowii and its fr...

Nancy T. Artinian, PhD, RN, FAHA, Chair; Gerald F. Fletcher, MD, FAHA, Co-Chair; Dariush Mozaffarian, MD, DrPH, FAHA; Penny Kris-Etherton, PhD, RD, FAHA; Linda Van Horn, PhD, RD, FAHA; Alice H. Lichtenstein, DSc, FAHA; Shiriki Kumanyika, PhD, MPH, FAHA; William E. Kraus, MD, FAHA; Jerome L. Fleg, MD, FAHA; Nancy S. Redeker, PhD, RN, FAHA; Janet C. Meininger, PhD, RN; JoAnne Banks, RN, PhD; Eile...

Based on previous studies that have shown flavonoids from the stems and leaves of Scutellaria baicalensis Georgi are neuroprotective agents in a naturally senile, D-galactose, aging in vivo model, as well as an in vitro model of oxidative/hypoxic injury, we established a cerebral ischemia/reperfusion model in rats by middle cerebral artery occlusion. The light/electron microscopic observations ...

There is a growing interest in the use of natural products like herbs, spices and plant extracts in the human food and animal feed industries. Scutellaria baicalensis Georgi from the Labiatae family is one of the fifty fundamental herbs of traditional Chinese medicine is thus used to treat a number of health disorders for over two thousand years. It is also called baical or chinese scutellaria ...

In the development process of a capital good, it should be decided how to maintain it once it is in the field. The level of repair analysis (LORA) is used to answer the questions: 1) which components to repair upon failure, and which to discard, 2) at which locations in the repair network to perform the repairs, and 3) at which locations to deploy resources, such as repair equipment. Next, it s...

Gene duplication could be beneficial by functional division but might increase the risk of genetic load. The dynamics of duplicated paralogs number could involve recombination, positive selection, and functional divergence. Duplication of DIHYDROFLAVONOL 4-REDUCTASE (DFR) has been reported in several organisms and may have been retained by escape from adaptive conflict (EAC). In this study, we ...

Introduction – Scutellaria lateriflora, commonly known as skullcap, is used as an ingredient in numerous herbal products. Unfortunately, it has occasionally been adulterated with Teucrium canadense or T. chamaedrys, commonly known as germander, which contains potentially hepatotoxic diterpenes. Chromatographic profiles of the phenolic components provide a means of distinguishing between these p...