clinical case reconstructed by Guido Majno (1975) from the Hippocratic records describes a wrestler who visits the iatreion (out-patient clinic) to be treated for a shoulder dislocation. With less invasive procedures no longer working to tighten the dislocation, the clinic adopts the drastic measure of inducing wound contraction by poking a hot needle through the skin of the armpit, and "in thi...

clinical case reconstructed by Guido Majno (1975) from the Hippocratic records describes a wrestler who visits the iatreion (out-patient clinic) to be treated for a shoulder dislocation. With less invasive procedures no longer working to tighten the dislocation, the clinic adopts the drastic measure of inducing wound contraction by poking a hot needle through the skin of the armpit, and "in thi...

purpose: to report a known case of leprosy with bilateral corneal scars. case report: we present a 70 year-old man who had developed claw hand deformity and loss of sensation in the extremities secondary to leprosy since 7 years ago. two years ago, he presented with loss of vision due to lagopthalmos and loss of corneal sensation for which he had undergone lateral tarsorrhaphy at the time. conc...

background: uterine rupture at the site of a previous cesarean scar is an uncommon but catastrophic complication of pregnancy, which is associated with significant maternal and fetal morbidity and mortality. case presentation: a 30-year old woman at 24th week of gestation and complaint of pain, contractions and spotting was admitted in royan institute in tehran, iran. she had a past medical his...

muscle fatigue assessment has been the basis of numerous studies, specifically, in neuromuscular rehabilitation and the applications of fessystems. various emgbased techniques, in time and frequency domains, have been investigatedover years for the detection and evaluationof this phenomenon. the main objective of this study has beento evaluate the efficiency of applying a number of techniques w...

(1) Objective: Keloid and hypertrophic scars are a challenge in clinical management, causing functional psychological discomfort. These pathological caused by proliferation of dermal tissue following skin injury. The TGF-β/Smad signal pathway the fibroblasts myofibroblasts is involved scarring process fibrosis. Today, multiple therapeutic strategies that target evaluated to attenuate aberrant s...

Hypertrophic scarring/hypertrophic scars (HS) is a highly prevalent condition following burns and trauma wounds. Numerous studies have demonstrated that transforming growth factor-β1 (TGF‑β1) plays an essential role in the wound healing process by regulating cell differentiation, collagen production and extracellular matrix degradation. The increased expression of TGF-β1 is believed to result i...

urinary tract infection (uti) is a common disease in childhood specially in female. in this study 50 patients with stablished diagnosis of uti were evaluated by both renal scan with tc-99m dmsa and renal sonography. the study revealed that most urinary tract infections are in children, female sex between 5-9 years of age. therefore the most important complications (renal scarring) are also comm...