نتایج جستجو برای: sample area
تعداد نتایج: 963786 فیلتر نتایج به سال:
We extend Lan and Trost’s (1997,1999) conditional power approach for interim sample size re-estimation to binary data for clinical trials with a noninferiority objective. If conditional power is used to extend a trial, the α level will be inflated. On the contrary if it is used to stop a trial early to claim futility, the α level will be reduced. If inflation does not exceed deflation, then the...
BACKGROUND Multiple infections are common in natural host populations and interspecific parasite interactions are therefore likely within a host individual. As they may seriously impact the circulation of certain parasites and the emergence and management of infectious diseases, their study is essential. In the field, detecting parasite interactions is rendered difficult by the fact that a larg...
BACKGROUND A survey was undertaken in 2007 to assess the prevalence and causes of blindness and visual impairment in people aged ≥ 50 years in three different counties in Jiangxi, South East China (Gao'an, Xin'gan and Wan'zai). The counties were purposively selected to assess the impact of established non-governmental organisation activities in two counties (Gao'an and Xin'gan) compared with a ...
OBJECTIVE To assess the correlation between presurgery neutrophil to lymphocyte ratio (NLR) and distant metastasis-free survival (DMFS) in patients with early breast cancer. DESIGN Retrospective analysis. PARTICIPANTS 300 Caucasian patients with early (T1-2, N0-1, non-metastatic) breast cancer who were followed from July 1999 to June 2015 at our Institution. MAIN OUTCOME MEASURES Distant ...
Some standard numerical problems become intractable in high dimensions. Yet successes are often achieved in practice. This may be explained in terms of the underlying target function being somehow simpler than assumed in the intractability arguments. A prototypical form of simplicity is approximate linearity. In moderate dimensions linearity can be investigated by linear regression. In very hig...
PURPOSE To determine the effect of optical defocus on the test-retest variability (TRV) of visual acuity measurements in normal subjects. METHODS Normal subjects underwent repeated visual acuity measurement with optical defocus of 0, 0.50, and 1.00 D. All measurements were taken using the Early Treatment Diabetic Retinopathy Study (ETDRS) version of the Bailey-Lovie logMAR chart. TRV was quan...
Background Infarct size is increasingly used as an efficacy endpoint in randomized trials comparing acute myocardial infarct (AMI) therapies. Infarct size, depicted by delayedenhancement-CMR, is quantified using manual planimetry (MANUAL), visual scoring (VISUAL), or automated techniques using signal-intensity thresholding to define infarct borders (AUTO). Although AUTO is considered the most r...
Introduction Forced medication is one of the most frequently used coercive measures in acute mental health units. It a practice that can lead to physical, psychological and psychopathological consequences. Therefore, it necessary implement reduce its use. In this sense, interesting study variables be associated with use, thus take accordingly. Objectives This attempts identify number forced epi...
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