Yan, an ETS family transcriptional repressor, is regulated by receptor tyrosine kinase signaling via the Ras/MAPK pathway. Phosphorylation and downregulation of Yan is facilitated by a protein called Mae. Yan and Mae interact through their SAM domains. We find that repression by Yan requires the formation of a higher order structure mediated by Yan-SAM polymerization. Moreover, a crystal struct...

This research was performed with the objective of evaluating the accuracy of spectral angle mapper (SAM) classification using different reference spectra. The Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) digital images were applied in the SAM classification in order to map the distribution of hydrothermally altered rocks in the Kerman Cenozoic magmatic arc (KCMA), Iran...

Diatoms are the major marine primary producers in the Southern Ocean and a key component of the carbon and silicate biogeochemical cycle. Using 15 years of satellite-derived diatom concentration from September to April (1997–2012), we examine the mean patterns and the interannual variability of the diatom bloom phenology in the Southern Ocean. Mean spatial patterns of timing and duration of dia...

Stimulus generalization is the tendency, after experience with a given stimulus, to react in the same way to other, similar stimuli. Shepard (1987) has proposed a universal law forstimulus generalization that deals with relations in a "psychological space," established through multidimensional curve-fitting techniques (MDS). These methods can discover the smallest number of dimensions such that...

Sam Wang is a pioneer in using statistical methods to analyze U.S. presidential election polls. In this election season interview with Neuron, he discusses diagnosing partisan gerrymandering, his research on the cerebellum, and how he analyzes polls with high accuracy.

We propose a new combination of the bivariate Shepard operators [10] by the three point Lidstone polynomials introduced in [12]. The new combination inherits both degree of exactness and Lidstone interpolation conditions at each node, which characterize the interpolation polynomial. These new operators …nd application to the scattered data interpolation problem when supplementary second order d...