BACKGROUND The use of negative pressure in the dressing of split skin grafts has been shown to promote healing by a variety of mechanisms, including a decrease in interstitial oedema, an increase in perfusion and a decrease in bacterial colonisation. Vacuum-assisted closure (VAC) dressings have, until now, been used as the archetype for negative pressure dressings and have been reflected as suc...

Bullous pemphigoid (BP) is the most common subepidermal autoimmune blistering skin disease seen in the elderly. The prognosis of BP is poor, since the 1-year mortality rate has been reported to range from 25% to 40% in recent studies [1]. Corticosteroids have been so far the mainstay of therapy [2]. Antibiotics and immunosuppressants, such as cyclophosphamide and azathioprine, have also been us...

We have developed a biodegradable temporizing matrix (BTM) capable of supporting secondary split-skin graft-take in animal studies. We report its first long-term implantation and use as a dermal scaffold in humans. This preliminary study assesses its ability to integrate, its ease of delamination, its ability to sustain split-skin graft in complex wounds, the degree of wound contraction, and ul...

salt stress is a factor limiting crop growth and productivity around the world. developing salt tolerant cultivars using desired plant features has been considered as a way to cope with the problem. in this study, a factorial experiment was used in order to determine the effects of salt stress on stomatal length at abaxial and adaxial leaf surfaces, relative water content (rwc) and transpiratio...