Thirty-three patients undergoing elective transurethral resection of the prostate were allocated randomly to receive either 0.9% isotonic saline 7 ml kg-1 (16 patients), or 3% hypertonic saline 7 ml kg-1 (17 patients) as a preload before spinal anaesthesia. After spinal anaesthesia, the incidence of systolic arterial pressure < 75% of control value was greater in the normal saline group than in...

BACKGROUND AND AIMS There is no evidence that the epinephrine-3% hypertonic saline combination is more effective than 3% hypertonic saline alone for treating infants hospitalized with acute bronchiolitis. We evaluated the efficacy of nebulized epinephrine in 3% hypertonic saline. PATIENTS AND METHODS We performed a randomized, double-blind, placebo-controlled clinical trial in 208 infants hos...

INTRODUCTION Hypertonic saline (HS) was introduced in our physician-based mobile emergency care unit (MECU) in September 2006 for patients with severe traumatic brain injury and hypotension. HS has, however, rarely been used and we sought to identify barriers to its implementation. MATERIAL AND METHODS We conducted a survey based on a questionnaire administered to all 40 anaesthesiologists em...

OBJECTIVE To compare the effects of topical mitomycin-C at different concentrations on submucosal collagen deposition on the vocal folds of swine. METHODS The animals were divided into three groups according to the composition of the topical solution to be applied to the vocal folds: 0.9% saline solution (control group); 4 mg/ml mitomycin-C (group 1) and 8 mg/ml mitomycin-C (group 2). Thirty ...

Infection with respiratory syncytial virus (RSV) is among the universal experiences of childhood. Worldwide, by 1 year of life, half of all children have been infected with RSV and by 2 years of age, virtually all children have been infected with RSV. Unlike many viral infections, it is the prevalence, as opposed to the severity, of infection that motivates our collective focus on the optimal t...

The present review discusses the hemodynamic and immune-modulatory effects of hypertonic saline in experimental shock and in patients with sepsis. We comment on the mechanisms of action of hypertonic saline, calling upon data in hemorrhagic and septic shock. Specific actions of hypertonic saline applicable to severe sepsis and septic shock are highlighted. Data available support potential benef...

High-throughput genomic technology has enabled us to screen the entire genome and generate hypotheses at relatively low costs. One of the driving forces in highthroughput genomic technology is high-throughput sequencing (HTS).With its rapid development and affordability, HTS has quickly become the go-to choice for interrogating the entire genome. The analysis methodology development for HTS has...

We studied two neonates fed diluted formula and excessive water who developed hyponatraemic convulsions; treatment included intravenous hypertonic saline and water restriction. Educating mothers is important to stop recurrences.

In the l i tera ture on tissue cul ture are repor ted , more or less completely, experiments test ing the effect of hypoton ic and hyper ton ic solutions upon growth of cells and upon individual cell s tructures. I t was wi th a view, therefore, of s tudying more fully the effect of solutions of different concentrat ions tha t the present work was undertaken. T h e experiments were performed in...