نتایج جستجو برای: salicylates
تعداد نتایج: 601 فیلتر نتایج به سال:
A B ST R A CT In man and other animals, urinary excretion of the histidine and histamine metabolite, imidazoleacetate, is increased and that of its conjugated metabolite, ribosylimidazoleacetate, decreased by salicylates. Imidazoleacetate has been reported to produce analgesia and narcosis. Its accumulation as a result of transferase inhibition could play a part in the therapeutic effects of sa...
Since Cochran and others (1950) reported the development of Cushing's syndrome in a 12-year-old girl receiving 5 g. aspirin daily for acute rheumatism, much work has focused on the possibility that the therapeutic and metabolic effects accompanying salicylate administration may be dependent upon the intermediary production of ACTH and/or adrenal corticoids. These authors noted frequent past ref...
OBJECTIVE To determine the efficacy and safety of topical rubefacients containing salicylates in acute and chronic pain. DATA SOURCES Electronic databases and manufacturers of salicylates. STUDY SELECTION Randomised double blind trials comparing topical rubefacients with placebo or another active treatment, in adults with acute or chronic pain, and reporting dichotomous information, around ...
It is increasingly accepted that chronic inflammation participates in obesity-induced insulin resistance and type 2 diabetes (T2D). Salicylates and thiazolidinediones (TZDs) both have anti-inflammatory and anti-hyperglycemic properties. The present study compared the effects of these drugs on obesity-induced inflammation in adipose tissue (AT) and AT macrophages (ATMs), as well as the metabolic...
Vestibular schwannomas (VSs) are the most common tumors of the cerebellopontine angle. Significant clinical need exists for pharmacotherapies against VSs. Motivated by previous findings that immunohistochemical expression of cyclooxygenase 2 (COX-2) correlates with VS growth rate, we investigated the role of COX-2 in VSs and tested COX-2 inhibiting salicylates against VSs. COX-2 was found to be...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید