Racecadotril is a guideline-recommended treatment to alleviate symptoms of acute diarrhea. A systematic review of randomized studies was performed comparing efficacy and safety of treatment with racecadotril to that with placebo or active treatments in adults. In five double-blind studies, racecadotril and placebo had comparable tolerability, but racecadotril was more effective. This was consis...

BACKGROUND Problems with currently recommended Helicobacter pylori eradication therapies include unsatisfactory eradication rates and/or therapy-associated side effects. AIM To investigate the effects of Saccharomyces boulardii as supplementation to standard triple therapy on H. pylori eradication rates and therapy-associated side effects. METHODS The Cochrane Library, MEDLINE and EMBASE da...

OBJECTIVE To compare the efficacy of Saccharomyces boulardii and lactic acid producing probiotics in addition to usual treatment regimen to cure diarrhea among children (6 months to 5 years of age). STUDY DESIGN Randomized controlled trial. PLACE AND DURATION OF STUDY Department of Pediatrics, Sheikh Zayed Hospital, Lahore, from February to July 2015. METHODOLOGY Children suffering from a...

Effect of Microencapsulation on the Viability Lactobacillus Acidophilus and Saccharomycess Boulardii Probiotics at Different Storage Temperatures in Doogh

BACKGROUND Recent advances in culture-independent approaches have enabled insights into the diversity, complexity, and individual variability of gut microbial communities. OBJECTIVES To examine the effect of oral administration of Saccharomyces (S.) boulardii and mode of delivery on the intestinal microbial community in preterm infants. STUDY DESIGN Stool samples were collected from preterm...

Health benefits attributed to probiotics have been described for decades. They include the treatment and the prevention of gastrointestinal diseases, vaginal and urinary infections and allergies. Saccharomyces boulardii, a species of yeast widely distributed, has been described as a biotherapeutic agent since several clinical trials displayed its beneficial effects in the prevention and the tre...

There is a growing concern regarding the recurrent observation of aflatoxins (AFs) in the milk of lactating animals. Regarding this, the present study was conducted to assess the aflatoxin M1 (AFM1)-binding ability of three species, namely Lactobacillus rhamnosus, L. plantarum, and Saccharomyces boulardii, inAFM1-contaminatedmilk. The mentioned species were a...

The anti-inflammatory cytokine interleukin-10 and its viral homologs were chosen as model proteins for the development of drug delivery systems based on probiotic carriers like E. coli Nissle 1917, E. coli G3/10, and Saccharomyces boulardii. Exterior cytokine secretion was achieved by a modified E. coli hemolysin transporter. Release of interleukin-10 transported to the periplasm via the OmpF s...

Introduction: The purpose of this study was formulation and preparation of a proper culture medium for Saccharomyces cerevisiae var. boulardii with molasses and animal serum. Methods: A fully-crossed factorial design contain 5%, 10% and 20% of molasses (M) with 0, 1% and 5% animal serum (S) was used in this study. The pH of all culture medias were adjusted to 5.6 with acetic acid. The seed was ...

Background DNA vaccines are a good option to generate a desired antigen using the cellular machinery of the vaccinated subject. This kind of vaccine can induce both of the humoral and cellular immune response, and show high stability and easy working, as well as offer a low-cost production. and safety for immune compromised patients [1]. However, some disadvantages, such as the low transfection...