background α-adrenergic receptor 2a (adra2a) and angiotensin-converting enzyme (ace) genes have been variably associated with obesity and its related phenotypes in different populations worldwide. objectives this cross-sectional study aims to investigate the association of adrenergic receptor α2a (adra2a) rs553668 and angiotensin-converting enzyme (ace) i/d single nucleotide polymorphisms (snps...

multiple sclerosis (ms) is an autoimmune disease characterized by recurrent episodes of demyelination and axonal lesion mediated by cd4+ t cells with a proinflammatory t helper (th)1 and th17 phenotypes, macrophages, and soluble inflammatory mediators. the overactive  pro-inflammatory  th1  cells  and  clonal  expansion  of  b  cells  initiate  an inflammatory cascade with several cellular and ...

background & aim: eucalyptus l'her. [an aromatic genera of the family (myrtaceae)] is native to australia and other tropical species is planted worldwide. the purpose of this study is to extract and identify the essential oils components of four species of eucalyptus l'her. cultivated in botanical garden of kashan, central iran. experimental: leaves of e. largiflorens, e. intertexta, ...

the essential oils isolated by hydrodistillation from the leaves of two eucalyptus gillii maiden and e. microcarpa subsp. macrocarpa hook were analysed by gc and gc/ms. the main components identified in e. gillii oil were 1, 8-cineole (79.5%), trans-pinocarveol (8%) and ?-pinene (2.7%), and in e. microcarpa were 1, 8-cineole (77.3%), ?-pinene (5.6%) and terpin-1-ol (5.1%). oils with high conten...

conclusions our study demonstrated that tgf-β1 serum levels is higher in osteoporotic postmenopausal females than non-osteoporotic ones, and probably aberrant increase in tgf-β1 in postmenopausal females can result in uncoupled bone resorption and formation, which leads to osteoporosis. background postmenopausal osteoporosis is a major cause of morbidity in postmenopausal females. transforming ...

introduction: evidence suggests that neuronal apoptosis in neurodegenerative diseases is correlated with inflammatory reactions. the beneficial or detrimental role of apoptosis in neuroinflammation is unclear. elucidating this question may be helpful in management of neurodegenerative diseases. since tnf-α is able to induce apoptosis as well as increased viability of the cells by activation of ...

in traditional chinese medicine, arsenous compounds, including arsenic trioxide (ato), are often used to treat many diseases, which are safe and effective. recently, studies have indicated that th17– il-17 involved in the pathogenesis and development of asthma. the goal of this study was to investigate the effect and mechanism of ato on asthma, especially the th17– il-17 axis. we used oval bumi...

objective(s): present study was performed in order to uncover new aspects for nicotine-induced damages on spermatogenesis cell lineage. materials and methods: for this purpose, 36 mature male wistar rats were divided into three groups as; control-sham (0.2 ml, saline normal, ip), low dose (0.2 mg/kg bw-1, ip) nicotine-received and high dose (0.4 mg/kg bw-1, ip) nicotine-received groups. followi...

b ackground: acanthamoeba spp . are free-living amoebae commonly found in the environmental sources such as water, soil, and air. this ubiquitous amoeba is the causative agent of amoebic kerati- tis (ak). the objective of the present study was to investigate the presence of acanthamoeba spp. in water and soil sources in ahvaz city, khuzestan province, southern iran. m ethods: in general, 110 sa...