نتایج جستجو برای: rvr
تعداد نتایج: 402 فیلتر نتایج به سال:
OBJECTIVE We investigated the impact of host genetics represented by the single nucleotide polymorphism (SNP) of the IL28B gene and viral genetic variations within the nonstructural protein 5A (NS5A) [including the interferon (IFN)/ribavirin (RBV) resistance-determining region (IRRDR) and the IFN sensitivity-determining region (ISDR)] on the outcome of pegylated IFN and RBV (PEG-IFN/RBV) treatm...
During exercise, reflex renal vasoconstriction helps maintain blood pressure and redistributes blood flow to the contracting muscle. Sex and muscle mass have been shown to influence certain cardiovascular responses to exercise. Whether sex and/or muscle mass influence renal vasoconstrictor responses to exercise is unknown. We studied healthy men (n = 10) and women (n = 10) matched for age and b...
OBJECTIVES The optimal treatment of hepatitis C virus (HCV) genotype 6 is unclear owing to its limited geographic distribution. Because of a high predictive value of rapid virological response (RVR) for sustained virological response (SVR), we conducted an open-label randomized controlled trial to compare 24- and 48-week peginterferon/ribavirin combination therapy for patients with HCV genotype...
OBJECTIVES We assessed the outcome of double-filtration plasmapheresis (DFPP) combined with pegylated interferon (PEG-IFN) and ribavirin (RBV) therapy in patients infected with hepatitis C virus (HCV)-1b whose HCV had not disappeared during PEG-IFN/RBV combination therapy, or who had relapsed after the end of the therapy. Additionally, we investigated factors predictive of sustained virological...
During exercise, muscle mechanoreflex-mediated sympathoexcitation evokes renal vasoconstriction. Animal studies suggest that prostaglandins generated within the contracting muscle sensitize muscle mechanoreflexes. Thus we hypothesized that local prostaglandin blockade would attenuate renal vasoconstriction during ischemic muscle stretch. Eleven healthy subjects performed static handgrip before ...
Power production from intermittent renewable energy resources, such as solar and wind, has increased in the past few decades, leading researchers engineers to establish techniques preserve a stable electrical grid. Consequently, hydraulic turbines are being used more frequently transient operating modes regulate The present work provides comprehensive numerical study on flow field of high-head ...
Abstract In this paper, we investigate the formation of Rotating Vortex Rope (RVR) using scale-resolving methods, SAS and Wall-Modeled LES (WMLES). We compare results from these simulation methods with experimental data Francis-99 workshop. This comparison shows that general features RVR can be captured both methods. However, WMLES would lead to a better quantitative agreement between velocity ...
We investigated whether tempol, a superoxide dismutase mimetic, affected renal hemodynamics and arterial pressure in spontaneously hypertensive rats (SHR) and Sprague-Dawley (SD) rats. We also examined whether tempol affected exaggerated renal vasoconstrictor responses to ANG II in SHR. To test whether the effects of tempol were due to a restored NO system, we used the NOS inhibitor N(w)-nitro-...
We recently demonstrated a direct relationship between autoregulation-related changes in renal vascular resistance (RVR) and renal interstitial ATP concentrations. To assess the possible role for extracellular ATP in the regulation of tubuloglomerular feedback (TGF)-mediated autoregulatory adjustments in RVR, renal interstitial ATP concentrations were measured with microdialysis probes in anest...
key factor in the successful application of a tunnel boring machine (TBM) in tunneling is the ability to develop accurate penetration rate estimates for determining project schedule and costs. Thus establishing a relationship between rock properties and TBM penetration rate can be very helpful in estimation of this vital parameter. However, this parameter cannot be simply predicted since there ...
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