نتایج جستجو برای: rs1298989 nr5a2

تعداد نتایج: 307  

Journal: :Cell 2011
Mathieu Gabut Payman Samavarchi-Tehrani Xinchen Wang Valentina Slobodeniuc Dave O'Hanlon Hoon-Ki Sung Manuel Alvarez Shaheynoor Talukder Qun Pan Esteban O. Mazzoni Stephane Nedelec Hynek Wichterle Knut Woltjen Timothy R. Hughes Peter W. Zandstra Andras Nagy Jeffrey L. Wrana Benjamin J. Blencowe

Alternative splicing (AS) is a key process underlying the expansion of proteomic diversity and the regulation of gene expression. Here, we identify an evolutionarily conserved embryonic stem cell (ESC)-specific AS event that changes the DNA-binding preference of the forkhead family transcription factor FOXP1. We show that the ESC-specific isoform of FOXP1 stimulates the expression of transcript...

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