DNA methylation is an epigenetic modification that plays a crucial role in normal mammalian development, retrotransposon silencing, and cellular reprogramming. Although methylation mainly occurs on the cytosine in a CG site, non-CG methylation is prevalent in pluripotent stem cells, brain, and oocytes. We previously identified non-CG methylation in several CG-rich regions in mouse germinal vesi...

Introduction: Erythrocytes are highly specialized and the most abundant cell type in vertebrates’ blood. Their main function is the transportation of oxygen to tissues of the body via hemoglobin. Methods: The study was aimed at evaluating erythrocyte morphology in Clarias gariepinus (Cg), Bufo bufo (Bb), and Agama agama (Aa) using different stains; Also, morphometric analysis of erythrocyte w...

Gabriel Taubin has graciously invited me to write this issue’s From the Editor column, giving me the opportunity to share my thoughts on what CG&A’s departments are, how they’re run, and why we hope you benefi t from them. In 2002, Jim Thomas, CG&A’s editor in chief at the time, asked me to serve as the associate editor in chief for departments. At the time, I wondered what I was getting myself...

The latest real-time graphics architectures include programmable floating-point vertex and fragment processors, with support for data-dependent control flow in the vertex processor. We present a programming language and a supporting system that are designed for programming these stream processors. The language follows the philosophy of C, in that it is a hardware-oriented, generalpurpose langua...

The Code Generation (CG) domain and its derivative domains, such as the CG56 domain (Motorola DSP56000) and the C language (CGC) domain, are used to generate code rather than to run simulations. Only the derivative domains are of practical use for generating code. The stars in the CG domain itself can be thought of as “comment generators”; they are useful for testing and debugging schedulers an...

In this paper, we evaluate the transferability of the coarse-grained (CG) force field (FF) of trans-1,4-polybutadiene which was built via a combined structure-based and thermodynamic quantity-based CG method at 413 K and 1 atm by systematically examining CG simulated structural and thermodynamic properties against the underlying atomistic simulation results at different temperatures. Interestin...