Contracts are a pragmatic tool for managing software systems, but programs using contracts suffer runtime overhead. If this overhead becomes a performance bottleneck, programmers must manually edit or remove their contracts. This is no good. Rather, the contracts should identify their own inefficiencies and remove unnecessary dynamic checks. Implementing contracts with Rosette is a promising wa...

The origin of animal multicellularity may be reconstructed by comparing animals with one of their closest living relatives, the choanoflagellate Salpingoeca rosetta. Just as animals develop from a single cell-the zygote-multicellular rosettes of S. rosetta develop from a founding cell. To investigate rosette development, we established forward genetics in S. rosetta. We find that the rosette de...

Erythrocytes infected with trophozoites or schizonts of Plasmodium falciparum bind uninfected erythrocytes, leading to rosette formation. Both established laboratory strains and fresh isolates from patients form such rosettes, but at widely different frequencies. IgG preparations from the serum of some P. falciparum-immune donors and heparin inhibited rosette formation. The results indicate tha...

" Agapeta zoegana oviposited significantly more on rosette and one-stem plants. " 2 plants had significantly greater A. zoegana larval density than 4 plants. " Significant correlation between the number of larvae infesting plant roots and Centaurea stoebe root diameter. " Cyphocleonus achates fed more frequently on multiple-stem 4 plants. " Arion lusitanicus had a strong feeding preference for ...

Ependymomas are well-delineated moderately cellular gliomas. Histolological features are perivascular pseudo rosettes and ependymal rosettes. WHO classification differentiate four major types: 1. Ependymoma and variants (grade II): Cellular ependymoma: a variant of ependymoma with conspicuous cellularity but often less prominent pseudo-rosette or rosette formation. Papillary ependymoma: a rare ...