نتایج جستجو برای: rna transfer
تعداد نتایج: 533631 فیلتر نتایج به سال:
Splicing of mammalian precursor transfer RNA (tRNA) molecules involves two enzymatic steps. First, intron removal by the tRNA splicing endonuclease generates separate 5' and 3' exons. In animals, the second step predominantly entails direct exon ligation by an elusive RNA ligase. Using activity-guided purification of tRNA ligase from HeLa cell extracts, we identified HSPC117, a member of the UP...
To better understand the role of protein synthesis in axons, we have identified the source of a portion of axonal RNA. We show that proximal segments of transected sciatic nerves accumulate newly-synthesized RNA in axons. This RNA is synthesized in Schwann cells because the RNA was labeled in the complete absence of neuronal cell bodies both in vitro and in vivo. We also demonstrate that the tr...
THE molecular properties of transfer ribonucleic acid @RNA) have been studied in many ways. Considerations of stability and the restrictive stereochemistry of nucleotides limit the number of possible tRNA models. Speculative models are useful here and may lead to an eventual solution of the tertiary structure of tRNA. Models of tRNA need to be defined in detail if they are to be tested against ...
Bronskill, P., Kennedy, T. D. & Lane, B. G. (1972) Biochim. Biophys. Acta 262,275-282 Dunn, D. B. (1963) Biochem. J. 8 6 , 1 4 ~ 1 5 ~ Dunn, D. B. & Flack, I. H. (1967) Abstr. FEBS Meet. 4th pp. 82 Dunn, D. B. & Flack, I. H. (1970) John Innes Institute Annual Report 61,7678 Fissekis, J. D. & Sweet, F. (1970) Biochemistry 9, 3136-3142 Gray, M. W. & Lane, B. G. (1968) Biochemistry 7,3441-3453 Ken...
The presence of the altered lysine transfer ribonucleic acid (tRNA) in Bacillus subtilis spores is strongly dependent on the medium on which the cells were sporulated. Cells sporulated on synthetic media or dilute complex media contain little or none of the new component, whereas those sporulated on concentrated complex media accumulate the altered tRNA. The accumulation begins during the fifth...
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