objective: to assess the effects of platelet rich plasma (prp) with chitosan biodegradable film on full thickness wound healing in rat. methods: this was an experimental study being performed in 2015 during a 4-month period. twenty-four male white wistar rats were divided into four groups of 12 rats each, randomly: control group (sham) with creation of wounds and no treatment, prp group with cr...

BACKGROUND Prolonged storage of platelets could improve availability and logistical management and decrease wastage. Immunobiochemical methods can be used to guarantee the quality of platelets after prolonged storage. OBJECTIVE The aim of this study was to compare storage-related changes in buffy coat-derived platelet concentrations versus platelet-rich plasmal. METHODS Units of whole blood...

introduction: nowadays the necessity of the existence of a certain width of keratinized gingiva is emphasized upon to maintain periodontal health and prevent soft tissue recession around teeth and dental implants. this study was carried out to compare two gingival graft procedures including connective tissue graft and graft with a combination of collagen sponge with platelet-rich plasma and pla...

objectives: platelets are anucleated fragments derived from megakaryocytes. it has been demonstrated that platelets play a role in hemostasis and innate immunity. in addition, platelets have a cd40 ligand which is an important molecular marker in motivating immune cells. thus, platelets also have a role in adaptive immunity as seen by their ability to activate b cells. since human platelet micr...

OBJECTIVE To perform a comparative analysis of the effects of platelet-rich plasma and centrifuged bone marrow aspirate on the induction of bone healing in rabbits. METHOD Twenty adult, male New Zealand rabbits were randomly separated into two equal groups, and surgery was performed to create a bone defect (a cortical orifice 3.3 mm in diameter) in the proximal metaphysis of each rabbit's rig...

Introduction Autologous plasma-rich platelet (PRP) is a human platelet concentrated product which is in low volume of plasma. Using PRP in rejuvenation and resolution of some cosmetic problems has been already popular in many countries and also in Iran. As no study performed in this field in Iran and regarding the high prevalence of using PRP in society with no validate references in the case ...

BACKGROUND Demineralized bone matrix is an osteoinductive and osteoconductive material that is often used in orthopaedic surgery to induce bone formation. Autologous platelet-rich plasma, which contains proliferative and chemoattractant growth factors, has been used as a demineralized bone matrix adjuvant with mixed results. One variable during clinical use appears to be whether the platelet-ri...

introduction: neuroblastoma is the most common extracranial solid tumor in children, accounting for 8% to 10% of all childhood cancers. significantly, autologous transplantation appeared to have the largest impact on survival for the high risk subset of patients, such as those with n-myc amplified metastatic disease diagnosed after age 2 years. patients and methods: this study includes high ris...

conclusions tissue engineering may open a new window in cleft palate reconstruction. stem cells and growth factors play key roles in this field. results we reported a summary of the key-points concerning cleft palate development, the genes involving this defect, current therapeutic strategies, recently novel aspects, and future advances in treatments for easy and fast understanding of the conce...

Purpose: The aim of this study was to compare a new method for the production of platelet-rich plasma (PRP), the plasma-rich-in-growth-factors kit (PRGF kit; G.A.C. Medicale San Antonio, Vitoria, Spain), with an established method, the Platelet Concentrate Collection System (PCCS; 3i/Implant Innovations, Palm Beach Gardens, FL) with respect to resulting cellular and growth factor contents. Mate...